![](/images/graphics-bg.png)
Diagnosis of Spontaneous Bacterial Peritonitis and an In Situ Hybridization Approach to Detect an “Unidentified” Pathogen
Joint Authors
Nishiguchi, Shuhei
Enomoto, Hirayuki
Inoue, Shin-ichi
Matsuhisa, Akio
Source
International Journal of Hepatology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Spontaneous bacterial peritonitis (SBP) is a frequent and severe complication in cirrhotic patients with ascites.
Although identifying the pathogen(s) plays a major role in the management of infectious diseases, ascitic fluid cultures often show negative results in patients with clinical signs and symptoms of SBP, and ascitic fluid cell analyses are the gold standard method for diagnosing SBP.
SBP is generally diagnosed based on an increased number of polymorphonuclear neutrophils in the ascitic fluid (>250/mm3), and the identification of the causal pathogen may not be given consideration.
We newly developed an in situ hybridization (ISH) method to provide early and direct evidence of bacterial infection in ascites in patients with SBP.
This paper will review the diagnosis of SBP, including our novel approach with ISH method to detect bacterial DNA in SBP ascitic fluid.
American Psychological Association (APA)
Enomoto, Hirayuki& Inoue, Shin-ichi& Matsuhisa, Akio& Nishiguchi, Shuhei. 2014. Diagnosis of Spontaneous Bacterial Peritonitis and an In Situ Hybridization Approach to Detect an “Unidentified” Pathogen. International Journal of Hepatology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-486871
Modern Language Association (MLA)
Enomoto, Hirayuki…[et al.]. Diagnosis of Spontaneous Bacterial Peritonitis and an In Situ Hybridization Approach to Detect an “Unidentified” Pathogen. International Journal of Hepatology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-486871
American Medical Association (AMA)
Enomoto, Hirayuki& Inoue, Shin-ichi& Matsuhisa, Akio& Nishiguchi, Shuhei. Diagnosis of Spontaneous Bacterial Peritonitis and an In Situ Hybridization Approach to Detect an “Unidentified” Pathogen. International Journal of Hepatology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-486871
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486871