Cardiorenal Syndrome Caused by Heart Failure with Preserved Ejection Fraction
Joint Authors
Tarquini, Roberto
Gensini, Gian Franco
Lazzeri, Chiara
Valente, Serafina
Source
International Journal of Nephrology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Since cardiorenal dysfunction is usually secondary to multiple factors acting in concert (and not only reduced cardiac output) in the present paper we are going to focus on the interrelationship between heart failure with normal ejection fraction and the development of cardiorenal syndrome.
The coexistence of renal impairment in heart failure with preserved ejection fraction (CRS type 2 and 4) is common especially in older females with hypertension and/or diabetes.
It can be hypothesized that the incidence of this disease association is growing, while clinical trials enrolling these patients are still lacking.
The main mechanisms thought to be involved in the pathophysiology of this condition are represented by the increase of intra-abdominal and central venous pressure and the activation of the renin-angiotensin system.
Differently from CRS in heart failure with reduced ejection fraction, the involvement of the kidney may be under-diagnosed in patients with heart failure and preserved ejection fraction and the optimal therapeutic strategy in this condition, though challenging, is far to be completely elucidated.
Further studies are needed to assess the best therapeutic regimen in patients with renal dysfunction (and worsening) and heart failure and preserved ejection fraction.
American Psychological Association (APA)
Lazzeri, Chiara& Valente, Serafina& Tarquini, Roberto& Gensini, Gian Franco. 2011. Cardiorenal Syndrome Caused by Heart Failure with Preserved Ejection Fraction. International Journal of Nephrology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-486898
Modern Language Association (MLA)
Lazzeri, Chiara…[et al.]. Cardiorenal Syndrome Caused by Heart Failure with Preserved Ejection Fraction. International Journal of Nephrology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-486898
American Medical Association (AMA)
Lazzeri, Chiara& Valente, Serafina& Tarquini, Roberto& Gensini, Gian Franco. Cardiorenal Syndrome Caused by Heart Failure with Preserved Ejection Fraction. International Journal of Nephrology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-486898
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486898