History of Cesarean Section Associated with Childhood Onset of T1DM in Newfoundland and Labrador, Canada
Joint Authors
Penney, S.
Gill, N.
Sikdar, K.
Phillips, J.
Newhook, L. A.
Source
Journal of Environmental and Public Health
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-08
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
Newfoundland and Labrador (NL) has one of the highest incidences of Type 1 diabetes mellitus (T1DM) worldwide.
Rates of T1DM are increasing and the search for environmental factors that may be contributing to this increase is continuing.
Methods.
This was a population-based case control design involving the linkage of data from a diabetes database with live birth registration data.
266 children aged 0–15 years with T1DM were compared to age- and gender-matched controls.
Chi-square analysis and multivariate conditional logistic regression were carried out to assess maternal and infant factors (including maternal age, marital status, education, T1DM, hypertension, birth order, delivery method, gestational age, size-for-gestational-age, and birth weight).
Results.
Cases of T1DM were more likely to be large-for-gestational-age (P=0.024) and delivered by C-section (P=0.009) as compared to controls.
C-section delivery was associated with increased risk of T1DM (HR 1.41, P=0.015) when birth weight and gestational age were included in the model, but not when size-for-gestational-age was included (HR 1.3, P=0.076).
Conclusions.
Birth by C-section was found to be a risk factor for the development of T1DM in a region with high rates of T1DM and birth by C-section.
These findings may have an impact on health practice, health care planning, and future research.
American Psychological Association (APA)
Phillips, J.& Gill, N.& Sikdar, K.& Penney, S.& Newhook, L. A.. 2012. History of Cesarean Section Associated with Childhood Onset of T1DM in Newfoundland and Labrador, Canada. Journal of Environmental and Public Health،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-486922
Modern Language Association (MLA)
Phillips, J.…[et al.]. History of Cesarean Section Associated with Childhood Onset of T1DM in Newfoundland and Labrador, Canada. Journal of Environmental and Public Health No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-486922
American Medical Association (AMA)
Phillips, J.& Gill, N.& Sikdar, K.& Penney, S.& Newhook, L. A.. History of Cesarean Section Associated with Childhood Onset of T1DM in Newfoundland and Labrador, Canada. Journal of Environmental and Public Health. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-486922
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486922