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Beta-Thalassemia in Iran : New Insight into the Role of Genetic Admixture and Migration
Joint Authors
Houshmand, Massoud
Rezaee, Ali Reza
Khalili, Elham
Banoei, Mohammad Mehdi
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Iran with an area of 1.648 million km2 is located between the Caspian Sea and the Persian Gulf.
The Iranian population consists of multiethnic groups that have been influenced by various invasions and migration throughout history.
Studies have revealed the presence of more than 47 different β-globin gene mutations responsible for β-Thalassemia in Iran.
This paper is an attempt to study the origin of β-Thalassemia mutations in different parts of Iran.
Distribution of β-Thalassemia mutations in Iran shows different patterns in different areas.
β-Thalassemia mutations have been a reflection of people and area in correlation with migration and origin of ancestors.
We compared the frequencies of β-globin mutations in different regions of Iran with those derived from neighboring countries.
The analysis provided evidence of complementary information about the genetic admixture and migration of some mutations, as well as the remarkable genetic classification of the Iranian people and ethnic groups.
American Psychological Association (APA)
Rezaee, Ali Reza& Banoei, Mohammad Mehdi& Khalili, Elham& Houshmand, Massoud. 2012. Beta-Thalassemia in Iran : New Insight into the Role of Genetic Admixture and Migration. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-486935
Modern Language Association (MLA)
Rezaee, Ali Reza…[et al.]. Beta-Thalassemia in Iran : New Insight into the Role of Genetic Admixture and Migration. The Scientific World Journal No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-486935
American Medical Association (AMA)
Rezaee, Ali Reza& Banoei, Mohammad Mehdi& Khalili, Elham& Houshmand, Massoud. Beta-Thalassemia in Iran : New Insight into the Role of Genetic Admixture and Migration. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-486935
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486935