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Lung Postmortem Autopsy Revealing Extramedullary Involvement in Multiple Myeloma Causing Acute Respiratory Distress Syndrome
Joint Authors
Ravinet, Aurélie
Aliane, Jugurtha
Bay, Jacques-Olivier
Constantin, Jean-Michel
Pascal, Julien
Tremblay, Aymeric
Guièze, Romain
Lemal, Richard
Guérin, Renaud
Dechelotte, Pierre
Perbet, Sébastien
Ledoux, Albane
Gayraud, Guillaume
Chaleteix, Carine
Bazin, Jean-Etienne
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-06
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Pulmonary involvement with multiple myeloma is rare.
We report the case of a 61-year-old man with past medical history of chronic respiratory failure with emphysema, and a known multiple myeloma (Durie and Salmon stage III B and t(4;14) translocation).
Six months after diagnosis and first line of treatment, he presented acute dyspnea with interstitial lung disease.
Computed tomography showed severe bullous emphysema and diffuse, patchy, multifocal infiltrations bilaterally with nodular character, small bilateral pleural effusions, mediastinal lymphadenopathy, and a known lytic lesion of the 12th vertebra.
He was treated with piperacillin-tazobactam, amikacin, oseltamivir, and methylprednisolone.
Finally, outcome was unfavourable.
Postmortem analysis revealed diffuse and nodular infracentimetric infiltration of the lung parenchyma by neoplastic plasma cells.
Physicians should be aware that acute respiratory distress syndrome not responding to treatment of common causes could be a manifestation of the disease, even with negative BAL or biopsy and could be promptly treated with salvage therapy.
American Psychological Association (APA)
Ravinet, Aurélie& Perbet, Sébastien& Guièze, Romain& Lemal, Richard& Guérin, Renaud& Gayraud, Guillaume…[et al.]. 2014. Lung Postmortem Autopsy Revealing Extramedullary Involvement in Multiple Myeloma Causing Acute Respiratory Distress Syndrome. Case Reports in Hematology،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-486943
Modern Language Association (MLA)
Ravinet, Aurélie…[et al.]. Lung Postmortem Autopsy Revealing Extramedullary Involvement in Multiple Myeloma Causing Acute Respiratory Distress Syndrome. Case Reports in Hematology No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-486943
American Medical Association (AMA)
Ravinet, Aurélie& Perbet, Sébastien& Guièze, Romain& Lemal, Richard& Guérin, Renaud& Gayraud, Guillaume…[et al.]. Lung Postmortem Autopsy Revealing Extramedullary Involvement in Multiple Myeloma Causing Acute Respiratory Distress Syndrome. Case Reports in Hematology. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-486943
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486943