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Pulmonary Complications following Cytoreductive Surgery and Perioperative Chemotherapy in 147 Consecutive Patients
Joint Authors
Chang, David
Sugarbaker, Paul H.
Preti, Vinicius
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-13
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Cytoreductive surgery (CRS) with hyperthermic perioperative chemotherapy (HIPEC) has become a treatment option for selected patients with peritoneal metastases (PMs) from gastrointestinal malignancies.
The purpose of this study is to evaluate our most recent data regarding pulmonary complications (respiratory distress, pleural effusion, and pneumonia) and attempt to identify risk factors associated with this management plan.
This study includes the most recent 4-year experience with appendiceal and colorectal carcinomatosis patients treated in a uniform manner between January 1, 2006 and December 31, 2009.
A prospective morbidity and mortality database was maintained and pulmonary adverse events were analyzed with special attention to subphrenic peritonectomy.
There were 147 consecutive patients with a mean age of 49.9 years.
Fourteen patients (10%) presented grades I–IV pulmonary complications for a total of 26 events.
The peritonectomy of right upper quadrant was performed in 74% and right plus left in 49% of the patients.
Statistically, there were no more pulmonary complications among patients submitted to peritoneal stripping of right or right and left hemidiaphragm as compared to no subdiaphragmatic peritonectomy (P=1.00 and P=0.58, resp.).
In an analysis of 18 quantitative indicators and clinical variables with pulmonary adverse events, only blood replacement greater than six units showed a significant correlation (P=0.0062).
Pulmonary adverse events were observed in 10% of patients having CRS and HIPEC.
Subphrenic peritonectomy was not a specific risk factor for developing these adverse events.
American Psychological Association (APA)
Preti, Vinicius& Chang, David& Sugarbaker, Paul H.. 2012. Pulmonary Complications following Cytoreductive Surgery and Perioperative Chemotherapy in 147 Consecutive Patients. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-486952
Modern Language Association (MLA)
Preti, Vinicius…[et al.]. Pulmonary Complications following Cytoreductive Surgery and Perioperative Chemotherapy in 147 Consecutive Patients. Gastroenterology Research and Practice No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-486952
American Medical Association (AMA)
Preti, Vinicius& Chang, David& Sugarbaker, Paul H.. Pulmonary Complications following Cytoreductive Surgery and Perioperative Chemotherapy in 147 Consecutive Patients. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-486952
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486952