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Characteristics of Suppressor Macrophages Induced by Mycobacterial and Protozoal Infections in relation to Alternatively Activated M2 Macrophages
Joint Authors
Maw, Win Win
Sano, Chiaki
Tatano, Yutaka
Tomioka, Haruaki
Shimizu, Toshiaki
Kanehiro, Yuichi
Source
Clinical and Developmental Immunology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-15
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
In the advanced stages of mycobacterial infections, host immune systems tend to change from a Th1-type to Th2-type immune response, resulting in the abrogation of Th1 cell- and macrophage-mediated antimicrobial host protective immunity.
Notably, this type of immune conversion is occasionally associated with the generation of certain types of suppressor macrophage populations.
During the course of Mycobacterium tuberculosis (MTB) and Mycobacterium avium-intracellulare complex (MAC) infections, the generation of macrophages which possess strong suppressor activity against host T- and B-cell functions is frequently encountered.
This paper describes the immunological properties of M1- and M2-type macrophages generated in tumor-bearing animals and those generated in hosts with certain microbial infections.
In addition, this paper highlights the immunological and molecular biological characteristics of suppressor macrophages generated in hosts with mycobacterial infections, especially MAC infection.
American Psychological Association (APA)
Tomioka, Haruaki& Tatano, Yutaka& Maw, Win Win& Sano, Chiaki& Kanehiro, Yuichi& Shimizu, Toshiaki. 2012. Characteristics of Suppressor Macrophages Induced by Mycobacterial and Protozoal Infections in relation to Alternatively Activated M2 Macrophages. Clinical and Developmental Immunology،Vol. 2012, no. 2012, pp.1-19.
https://search.emarefa.net/detail/BIM-486963
Modern Language Association (MLA)
Tomioka, Haruaki…[et al.]. Characteristics of Suppressor Macrophages Induced by Mycobacterial and Protozoal Infections in relation to Alternatively Activated M2 Macrophages. Clinical and Developmental Immunology No. 2012 (2012), pp.1-19.
https://search.emarefa.net/detail/BIM-486963
American Medical Association (AMA)
Tomioka, Haruaki& Tatano, Yutaka& Maw, Win Win& Sano, Chiaki& Kanehiro, Yuichi& Shimizu, Toshiaki. Characteristics of Suppressor Macrophages Induced by Mycobacterial and Protozoal Infections in relation to Alternatively Activated M2 Macrophages. Clinical and Developmental Immunology. 2012. Vol. 2012, no. 2012, pp.1-19.
https://search.emarefa.net/detail/BIM-486963
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486963