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Use of Animal Models to Investigate Major Allergens Associated with Food Allergy
Joint Authors
Meeusen, Els N. T.
O'Hehir, Robyn E.
Bischof, Robert J.
de Veer, Michael J.
Van Gramberg, Jenna L.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-11
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Food allergy is an emerging epidemic that affects all age groups, with the highest prevalence rates being reported amongst Western countries such as the United States (US), United Kingdom (UK), and Australia.
The development of animal models to test various food allergies has been beneficial in allowing more rapid and extensive investigations into the mechanisms involved in the allergic pathway, such as predicting possible triggers as well as the testing of novel treatments for food allergy.
Traditionally, small animal models have been used to characterise immunological pathways, providing the foundation for the development of numerous allergy models.
Larger animals also merit consideration as models for food allergy as they are thought to more closely reflect the human allergic state due to their physiology and outbred nature.
This paper will discuss the use of animal models for the investigation of the major food allergens; cow's milk, hen's egg, and peanut/other tree nuts, highlight the distinguishing features of each of these models, and provide an overview of how the results from these trials have improved our understanding of these specific allergens and food allergy in general.
American Psychological Association (APA)
Van Gramberg, Jenna L.& de Veer, Michael J.& O'Hehir, Robyn E.& Meeusen, Els N. T.& Bischof, Robert J.. 2013. Use of Animal Models to Investigate Major Allergens Associated with Food Allergy. Journal of Allergy،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-486980
Modern Language Association (MLA)
Van Gramberg, Jenna L.…[et al.]. Use of Animal Models to Investigate Major Allergens Associated with Food Allergy. Journal of Allergy No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-486980
American Medical Association (AMA)
Van Gramberg, Jenna L.& de Veer, Michael J.& O'Hehir, Robyn E.& Meeusen, Els N. T.& Bischof, Robert J.. Use of Animal Models to Investigate Major Allergens Associated with Food Allergy. Journal of Allergy. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-486980
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-486980