Assessment of Early Cognitive Impairment in Patients with Clinically Isolated Syndromes and Multiple Sclerosis
Joint Authors
Sağduyu Kocaman, Ayşe
Ekmekçi, Özgül
Baysal Kıraç, Leyla
Yüceyar, Nur
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-14
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
The aim of our study was to investigate the frequency and pattern of cognitive impairment in patients with clinically isolated syndromes and definite diagnosis of multiple sclerosis within the last 2 years.
Methods.
We assessed the cognitive status of 46 patients aged 18–49 years with clinically isolated syndromes or definite diagnosis of multiple sclerosis who have onset of their symptoms within the last 2 years.
Patients were matched with 40 healthy participants for age, sex, and educational level.
Neuropsychological assessment was performed by stroop test, paced auditory serial addition test (PASAT), controlled oral word association test (COWAT), clock drawing test, trail making test (TMT), faces symbol test (FST).
Hamilton Depression Scale and Modified Fatigue Impact Scale were used to quantify the severity of any depression and fatigue the subjects might suffer.
Results.
19.6% of early MS/CIS group failed at 4 and more tests and had significant cognitive impairment focused on attention, executive functions, memory, and learning.
No significant relationship was found between cognitive impairment and disability and fatigue scores.
Discussion.
Cognitive impairment can be present from the earliest stage of multiple sclerosis.
It should be considered among the main manifestations of MS even in the earliest stages of the disease.
American Psychological Association (APA)
Baysal Kıraç, Leyla& Ekmekçi, Özgül& Yüceyar, Nur& Sağduyu Kocaman, Ayşe. 2014. Assessment of Early Cognitive Impairment in Patients with Clinically Isolated Syndromes and Multiple Sclerosis. Behavioural Neurology،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-487161
Modern Language Association (MLA)
Baysal Kıraç, Leyla…[et al.]. Assessment of Early Cognitive Impairment in Patients with Clinically Isolated Syndromes and Multiple Sclerosis. Behavioural Neurology No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-487161
American Medical Association (AMA)
Baysal Kıraç, Leyla& Ekmekçi, Özgül& Yüceyar, Nur& Sağduyu Kocaman, Ayşe. Assessment of Early Cognitive Impairment in Patients with Clinically Isolated Syndromes and Multiple Sclerosis. Behavioural Neurology. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-487161
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487161