Applying New Research Criteria for Diagnosis of Early Alzheimer's Disease : Sex and Intelligence Matter
Joint Authors
Beinhoff, U.
Tumani, Hayrettin
Riepe, Matthias W.
Source
International Journal of Alzheimer's Disease
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-08-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Alzheimer's disease (AD) can be diagnosed according to new research criteria proposed recently (Dubois et al., 2007).
Diagnosis is made on grounds of episodic memory deficits and one pathological biomarker: cerebrospinal fluid (CSF) or structural/functional imaging.
Goal was to investigate the dependence of episodic memory function on material (verbal, visuospatial), gender and premorbid intellectual ability (IQ).
The new research criteria of AD were applied retrospectively using data of 68 patients (Mini-Mental-Status Examination, MMSE ≥ 22) from a university memory clinic.
Women with lower IQ performed worse on visuospatial episodic memory than women with higher IQ and men with the same IQ.
Thus, women with lower IQ appear to be particularly vulnerable to visuospatial episodic memory deficits despite similar CSF tau values indicating a similar activity of the neurodegenerative process.
Gender, premorbid IQ, and visuospatial material need to be considered in the assessment of episodic memory breakdown applying the newly proposed research criteria for the diagnosis of AD.
American Psychological Association (APA)
Beinhoff, U.& Tumani, Hayrettin& Riepe, Matthias W.. 2009. Applying New Research Criteria for Diagnosis of Early Alzheimer's Disease : Sex and Intelligence Matter. International Journal of Alzheimer's Disease،Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-487208
Modern Language Association (MLA)
Beinhoff, U.…[et al.]. Applying New Research Criteria for Diagnosis of Early Alzheimer's Disease : Sex and Intelligence Matter. International Journal of Alzheimer's Disease No. 2009 (2009), pp.1-6.
https://search.emarefa.net/detail/BIM-487208
American Medical Association (AMA)
Beinhoff, U.& Tumani, Hayrettin& Riepe, Matthias W.. Applying New Research Criteria for Diagnosis of Early Alzheimer's Disease : Sex and Intelligence Matter. International Journal of Alzheimer's Disease. 2009. Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-487208
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487208