Bilateral Primary Adrenal Lymphoma Presenting with Adrenal Insufficiency
Joint Authors
Holm, Jakob
Friberg Hitz, Mette
Breum, Leif
Stenfeldt, Katrine
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-04
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Lymphoma may occasionally involve the adrenal glands, but primary adrenal lymphoma (PAL) is very rare and only few cases have been reported.
We present a case of a 60-year-old, otherwise healthy, woman, with bilateral PAL presenting with adrenal insufficiency.
The patient responded initially upon administration of large doses of intravenously hydrocortisone with total remission of symptoms.
An abdominal computerized tomography scan demonstrated bilateral adrenal lesions but did not demonstrate any other pathology.
Since metastatic malignant disease was suspected a positron-emission-tomography scan was performed only showing significant uptake in the adrenal glands.
Endocrine evaluation did not reveal abnormal function of any hormonal system and the patient was scheduled for bilateral adrenalectomy.
However the clinical condition deteriorated rapidly and the patient was readmitted to hospital before surgery was performed.
A new computerized tomography scan showed rapid progression of disease with further enlargement of the adrenal masses and both pulmonary and hepatic metastasis.
Needle biopsy was performed but the patient refused further treatment and died before a diagnosis was obtained.
The immuneohistochemical diagnosis was large B-cell lymphoma.
This case should remind clinicians that PAL may be a cause of bilateral adrenal incidentaloma especially if the patient presents with adrenal insufficiency.
American Psychological Association (APA)
Holm, Jakob& Breum, Leif& Stenfeldt, Katrine& Friberg Hitz, Mette. 2012. Bilateral Primary Adrenal Lymphoma Presenting with Adrenal Insufficiency. Case Reports in Endocrinology،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-487232
Modern Language Association (MLA)
Holm, Jakob…[et al.]. Bilateral Primary Adrenal Lymphoma Presenting with Adrenal Insufficiency. Case Reports in Endocrinology No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-487232
American Medical Association (AMA)
Holm, Jakob& Breum, Leif& Stenfeldt, Katrine& Friberg Hitz, Mette. Bilateral Primary Adrenal Lymphoma Presenting with Adrenal Insufficiency. Case Reports in Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-487232
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487232