Maternal β-Hemolytic Streptococcal Pharyngeal Exposure and Colonization in Pregnancy
Joint Authors
Eghtesady, Pirooz
Hathcock, Trupti
Hall, Matthew
Goessling, Lisa S.
Brar, Anoop K.
Epstein, Deirdre
Heidari-Bateni, Giv
Cunningham, Madeleine W.
Source
Infectious Diseases in Obstetrics and Gynecology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-20
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
To report the pharyngeal colonization rate of β-hemolytic streptococci and changes in the value of antistreptolysin O (ASO) and anti-DNase B serology titers during pregnancy.
Methods.
Healthy pregnant women were recruited and blood was drawn in each trimester.
The upper limit of normal (ULN) values for ASO and anti-DNase B was calculated for each trimester.
Throat swabs were collected for culture and positive cultures were further assessed for the identification of serogroup of the isolated β-hemolytic streptococcus.
Results.
Out of a total of 126 pregnant women, 34.1% had positive throat cultures.
Group C and group G strains were isolated in 18.2% of throat cultures while group F was detected in 13.5% of cases.
The rate of colonization with GAS was 1.6%.
There was an overall drop in ASO titer during pregnancy while anti-DNase B titers remained relatively unchanged.
ULN values of 164IU, 157IU, and 156IU were calculated for ASO at the first, second, and third trimesters, respectively.
Based on the ULN values, 28.6% of patients had recent streptococcal exposure.
Conclusions.
These results show that pregnant women act as a reservoir for spreading potentially immunogenic (groups C and G) and disease producing (group F) virulent strains of streptococci.
American Psychological Association (APA)
Heidari-Bateni, Giv& Brar, Anoop K.& Hall, Matthew& Hathcock, Trupti& Epstein, Deirdre& Goessling, Lisa S.…[et al.]. 2014. Maternal β-Hemolytic Streptococcal Pharyngeal Exposure and Colonization in Pregnancy. Infectious Diseases in Obstetrics and Gynecology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-487300
Modern Language Association (MLA)
Heidari-Bateni, Giv…[et al.]. Maternal β-Hemolytic Streptococcal Pharyngeal Exposure and Colonization in Pregnancy. Infectious Diseases in Obstetrics and Gynecology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-487300
American Medical Association (AMA)
Heidari-Bateni, Giv& Brar, Anoop K.& Hall, Matthew& Hathcock, Trupti& Epstein, Deirdre& Goessling, Lisa S.…[et al.]. Maternal β-Hemolytic Streptococcal Pharyngeal Exposure and Colonization in Pregnancy. Infectious Diseases in Obstetrics and Gynecology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-487300
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487300