Subcutaneous Panniculitis-Like T-Cell Lymphoma (SPTL)‎ in a Child with Spontaneous Resolution

Abstract EN

Subcutaneous panniculitis-like T-cell lymphomas (SPTLs) α/β are rare in childhood.

The present report refers to a case of a 7-year-old male child presenting an extensive skin lesion that began when he was 5 years of age.

Two biopsies were evaluated using the CD3, CD4, CD8, CD56, βF1, and TIA markers.

A dense infiltrate of CD3+, CD4−, CD8+, CD56−, βF1+, and TIA+ pleomorphic lymphocytes was found in the subcutis.

The previous biopsy showed cytophagic histiocytic panniculitis with a small focus on CD8+ and βF1+ malignant cells.

The lesion regressed spontaneously.

This case shows that prognosis may be excellent in SPTL (α/β).

On the other hand, it also serves as an alert that a biopsy performed in an area of cytophagic panniculitis may lead to misdiagnosis.