Diagnosis of Cryptococcosis and Prevention of Cryptococcal Meningitis Using a Novel Point-of-Care Lateral Flow Assay
Author
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-12
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Despite access to antiretroviral therapy, mortality from cryptococcal meningitis (CM) is high among persons with advanced HIV infection in sub-Saharan Africa.
Cryptococcal antigen (CrAg) is present several weeks to months before the onset of symptoms of meningitis and can be screened to prevent life threatening meningitis.
Recently, the World Health Organisation recommended that a new rapid CrAg lateral flow ‘‘dipstick’’ assay (LFA) is to be used to screen HIV-infected persons with CD4 counts of less than 100 cells/µL.
In this paper, we describe two cases of cryptococcosis with differing outcomes.
In the first case, the new CrAg LFA was used as part of a screen and preemptive treatment strategy to prevent CM.
In the second case, our patient had no access to the CrAg LFA and subsequently developed life threatening meningitis.
To the best of our knowledge, this is the first case report of cryptococcosis diagnosed using this novel assay.
American Psychological Association (APA)
Dhana, Ashar. 2013. Diagnosis of Cryptococcosis and Prevention of Cryptococcal Meningitis Using a Novel Point-of-Care Lateral Flow Assay. Case Reports in Medicine،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-487395
Modern Language Association (MLA)
Dhana, Ashar. Diagnosis of Cryptococcosis and Prevention of Cryptococcal Meningitis Using a Novel Point-of-Care Lateral Flow Assay. Case Reports in Medicine No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-487395
American Medical Association (AMA)
Dhana, Ashar. Diagnosis of Cryptococcosis and Prevention of Cryptococcal Meningitis Using a Novel Point-of-Care Lateral Flow Assay. Case Reports in Medicine. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-487395
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487395