Analysis of the Associations between Vitamin D and Albuminuria or β-Cell Function in Chinese Type 2 Diabetes
Joint Authors
Cai, Xiaoling
Ji, Linong
Hu, Zhaoheng
Han, Xueyao
Chen, Ling
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
To investigate the associations of 25-(OH)D and β-cell function or insulin resistance or albuminuria in Chinese type 2 diabetic patients.
Methods.
In total, 1408 type 2 diabetic patients without vitamin D supplement were included in this retrospective study.
Results.
Comparison between patients with and without 25-(OH)D deficiency indicated that, compared with patients with 25-(OH)D ≥ 50 nmol/L, patients with 25-(OH)D < 50 nmol/L showed a higher level of urine albumin-creatinine ratio (ACR) (90.15±10.30 mg/g versus 52.79±14.97 mg/g).
Multiple regression analysis indicated that 25-(OH)D was independently and negatively correlated with urine ACR (OR=0.985, 95%CI 0.972–0.999, P=0.03), adjusted by age, diabetic duration, HBP duration, SBP, HbA1c, creatinine, LDL-C, triglyceride, total cholesterol, and HDL-C.
Compared with patients with normal level of urine ACR, patients with higher level of urine ACR showed a significant lower level of 25-(OH)D (34.49±13.52 nmol/L versus 37.46±13.6 nmol/L, P=0.00).
Analysis of the associations of 25-(OH)D and β-cell function or insulin resistance showed that 25-(OH)D may not correlate with β-cell function or insulin resistance.
Conclusion.
25-(OH)D was independently associated with albuminuria in Chinese type 2 diabetic patients but was not associated with β-cell function or insulin resistance.
American Psychological Association (APA)
Cai, Xiaoling& Hu, Zhaoheng& Chen, Ling& Han, Xueyao& Ji, Linong. 2014. Analysis of the Associations between Vitamin D and Albuminuria or β-Cell Function in Chinese Type 2 Diabetes. BioMed Research International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-487466
Modern Language Association (MLA)
Cai, Xiaoling…[et al.]. Analysis of the Associations between Vitamin D and Albuminuria or β-Cell Function in Chinese Type 2 Diabetes. BioMed Research International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-487466
American Medical Association (AMA)
Cai, Xiaoling& Hu, Zhaoheng& Chen, Ling& Han, Xueyao& Ji, Linong. Analysis of the Associations between Vitamin D and Albuminuria or β-Cell Function in Chinese Type 2 Diabetes. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-487466
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487466