![](/images/graphics-bg.png)
Acylation Modification of Antheraea pernyi Silk Fibroin Using Succinic Anhydride and Its Effects on Enzymatic Degradation Behavior
Joint Authors
Ma, Caili
Yang, Weichao
Zhang, Ceng
Li, Xiufang
Wang, Lingshuang
Li, Mingzhong
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The degradation rate of tissue engineering scaffolds should match the regeneration rate of new tissues.
Controlling the degradation behavior of silk fibroin is an important subject for silk-based tissue engineering scaffolds.
In this study, Antheraea pernyi silk fibroin was successfully modified with succinic anhydride and then characterized by zeta potential, ninhydrin method, and FTIR.
In vitro, three-dimensional scaffolds prepared with modified silk fibroin were incubated in collagenase IA solution for 18 days to evaluate the impact of acylation on the degradation behavior.
The results demonstrated that the degradation rate of modified silk fibroin scaffolds was more rapid than unmodified ones.
The content of the β-sheet structure in silk fibroin obviously decreased after acylation, resulting in a high degradation rate.
Above all, the degradation behavior of silk fibroin scaffolds could be regulated by acylation to match the requirements of various tissues regeneration.
American Psychological Association (APA)
Li, Xiufang& Zhang, Ceng& Wang, Lingshuang& Ma, Caili& Yang, Weichao& Li, Mingzhong. 2013. Acylation Modification of Antheraea pernyi Silk Fibroin Using Succinic Anhydride and Its Effects on Enzymatic Degradation Behavior. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-487467
Modern Language Association (MLA)
Li, Xiufang…[et al.]. Acylation Modification of Antheraea pernyi Silk Fibroin Using Succinic Anhydride and Its Effects on Enzymatic Degradation Behavior. Journal of Chemistry No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-487467
American Medical Association (AMA)
Li, Xiufang& Zhang, Ceng& Wang, Lingshuang& Ma, Caili& Yang, Weichao& Li, Mingzhong. Acylation Modification of Antheraea pernyi Silk Fibroin Using Succinic Anhydride and Its Effects on Enzymatic Degradation Behavior. Journal of Chemistry. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-487467
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487467