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Pruritic Vesicular Eruption on the Lower Legs in a Diabetic Female
Joint Authors
al-Mannai, Haya
Abu Shaikha, Samya
Mansour, Khaled
al-Ansari, Hamda
Riad, Hassan
al-Sada, Hussein
al-Dosari, Sharifa
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
A 50-year-old diabetic female presented with highly pruritic vesicles and excoriated lesions over the anterior aspect of both lower legs.
The lesions were recurrent over the last two years.
She received a lot of medications with partial response.
Hb A1c was 10.8% (normal up to 7%).
CBC showed microcytic, hypochromic anemia.
Serum zinc, folate, IgE, TSH and T4 were all within normal ranges.
Biopsy showed epidermal separation secondary to keratinocyte necrosis and minimal monocytic, perivascular infiltrate.
Direct immunofluorescence was negative for intraepidermal and subepidremal deposition of immunoglobulin.
The dermis was positive for mucin deposition stainable by both PAS and Alcian blue while it was negative for Congo red and APC immunoperoxidase staining for amyloid material.
In conclusion, the case was diagnosed as bullosis diabeticorum by distinctive clinical and pathological features and after exclusion of other possible differentials.
Pruritus was partially controlled by topical potent steroid and the case was resolved spontaneously after eight months.
American Psychological Association (APA)
Riad, Hassan& al-Ansari, Hamda& Mansour, Khaled& al-Mannai, Haya& al-Sada, Hussein& Abu Shaikha, Samya…[et al.]. 2013. Pruritic Vesicular Eruption on the Lower Legs in a Diabetic Female. Bioinorganic Chemistry and Applications،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-487512
Modern Language Association (MLA)
Riad, Hassan…[et al.]. Pruritic Vesicular Eruption on the Lower Legs in a Diabetic Female. Bioinorganic Chemistry and Applications No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-487512
American Medical Association (AMA)
Riad, Hassan& al-Ansari, Hamda& Mansour, Khaled& al-Mannai, Haya& al-Sada, Hussein& Abu Shaikha, Samya…[et al.]. Pruritic Vesicular Eruption on the Lower Legs in a Diabetic Female. Bioinorganic Chemistry and Applications. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-487512
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487512