Implementing the Brazilian Database on Orofacial Clefts
Joint Authors
Félix, Têmis Maria
Fontes, Marshall Ítalo Barros
Bueno, Bruna Henrique
Magna, Luis Alberto
Gil-da-Silva-Lopes, Vera Lúcia
Leal, Gabriela Ferraz
Ribeiro, Erlane Marques
Mossey, Peter Anthony
Monlleó, Isabella Lopes
Fett-Conte, Agnes Cristina
de Souza, Josiane
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-12
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
High-quality clinical and genetic descriptions are crucial to improve knowledge of orofacial clefts and support specific healthcare polices.
The objective of this study is to discuss the potential and perspectives of the Brazilian Database on Orofacial Clefts.
Methods.
From 2008 to 2010, clinical and familial information on 370 subjects was collected by geneticists in eight different services.
Data was centrally processed using an international system for case classification and coding.
Results.
Cleft lip with cleft palate amounted to 198 (53.5%), cleft palate to 99 (26.8%), and cleft lip to 73 (19.7%) cases.
Parental consanguinity was present in 5.7% and familial history of cleft was present in 26.3% subjects.
Rate of associated major plus minor defects was 48% and syndromic cases amounted to 25% of the samples.
Conclusions.
Overall results corroborate the literature.
Adopted tools are user friendly and could be incorporated into routine patient care.
The BDOC exemplifies a network for clinical and genetic research.
The data may be useful to develop and improve personalized treatment, family planning, and healthcare policies.
This experience should be of interest for geneticists, laboratory-based researchers, and clinicians entrusted with OC worldwide.
American Psychological Association (APA)
Monlleó, Isabella Lopes& Fontes, Marshall Ítalo Barros& Ribeiro, Erlane Marques& de Souza, Josiane& Leal, Gabriela Ferraz& Félix, Têmis Maria…[et al.]. 2013. Implementing the Brazilian Database on Orofacial Clefts. Plastic Surgery International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-487524
Modern Language Association (MLA)
Monlleó, Isabella Lopes…[et al.]. Implementing the Brazilian Database on Orofacial Clefts. Plastic Surgery International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-487524
American Medical Association (AMA)
Monlleó, Isabella Lopes& Fontes, Marshall Ítalo Barros& Ribeiro, Erlane Marques& de Souza, Josiane& Leal, Gabriela Ferraz& Félix, Têmis Maria…[et al.]. Implementing the Brazilian Database on Orofacial Clefts. Plastic Surgery International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-487524
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487524