Preoperative Gadoxetic Acid-Enhanced MRI and Simultaneous Treatment of Early Hepatocellular Carcinoma Prolonged Recurrence-Free Survival of Progressed Hepatocellular Carcinoma Patients after Hepatic Resection
Joint Authors
Sano, Katsuhiro
Matsuda, Masanori
Maki, Akira
Watanabe, Mitsuaki
Amemiya, Hidetake
Fujii, Hideki
Kono, Hiroshi
Motosugi, Utaroh
Kawaida, Hiromichi
Ichikawa, Tomoaki
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background/Purpose.
The purpose of this study was to clarify whether preoperative gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) and simultaneous treatment of suspected early hepatocellular carcinoma (eHCC) at the time of resection for progressed HCC affected patient prognosis following hepatic resection.
Methods.
A total of 147 consecutive patients who underwent their first curative hepatic resection for progressed HCC were enrolled.
Of these, 77 patients underwent EOB-MRI (EOB-MRI (+)) before hepatic resection and the remaining 70 patients did not (EOB-MRI (−)).
Suspected eHCCs detected by preoperative imaging were resected or ablated at the time of resection for progressed HCC.
Results.
The number of patients who underwent treatment for eHCCs was significantly higher in the EOB-MRI (+) than in the EOB-MRI (−) (17 versus 6; P=0.04).
Recurrence-free survival (1-, 3-, and 5-year; 81.4, 62.6, 48.7% versus 82.1, 41.5, 25.5%, resp., P<0.01), but not overall survival (1-, 3-, and 5-year; 98.7, 90.7, 80.8% versus 97.0, 86.3, 72.4%, resp., P=0.38), was significantly better in the EOB-MRI (+).
Univariate and multivariate analyses showed that preoperative EOB-MRI was one of the independent factors significantly correlated with better recurrence-free survival.
Conclusions.
Preoperative EOB-MRI and simultaneous treatment of eHCC prolonged recurrence-free survival after hepatic resection.
American Psychological Association (APA)
Matsuda, Masanori& Ichikawa, Tomoaki& Amemiya, Hidetake& Maki, Akira& Watanabe, Mitsuaki& Kawaida, Hiromichi…[et al.]. 2014. Preoperative Gadoxetic Acid-Enhanced MRI and Simultaneous Treatment of Early Hepatocellular Carcinoma Prolonged Recurrence-Free Survival of Progressed Hepatocellular Carcinoma Patients after Hepatic Resection. HPB Surgery،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-487541
Modern Language Association (MLA)
Matsuda, Masanori…[et al.]. Preoperative Gadoxetic Acid-Enhanced MRI and Simultaneous Treatment of Early Hepatocellular Carcinoma Prolonged Recurrence-Free Survival of Progressed Hepatocellular Carcinoma Patients after Hepatic Resection. HPB Surgery No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-487541
American Medical Association (AMA)
Matsuda, Masanori& Ichikawa, Tomoaki& Amemiya, Hidetake& Maki, Akira& Watanabe, Mitsuaki& Kawaida, Hiromichi…[et al.]. Preoperative Gadoxetic Acid-Enhanced MRI and Simultaneous Treatment of Early Hepatocellular Carcinoma Prolonged Recurrence-Free Survival of Progressed Hepatocellular Carcinoma Patients after Hepatic Resection. HPB Surgery. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-487541
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487541