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Baseline Factors Predictive of SLT Response : A Prospective Study
Joint Authors
Lesk, Mark R.
Bruen, Robin
Harasymowycz, Paul
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose.
To study the response to Selective Laser Trabeculoplasty (SLT) according to baseline medical treatment, angle pigmentation, age, diagnosis (open-angle glaucoma or ocular hypertension), and baseline intraocular pressure (IOP).
Methods.
74 eyes of 74 patients were enrolled in this study.
Baseline characteristics were recorded for each patient.
IOP in the treated and fellow eyes was measured at baseline, and 1 month, 6 months, and 12 months following SLT.
IOP changes in the different groups were compared using two-way ANOVA and Pearson's correlation.
Results.
The mean age of our cohort was 71±10 years.
The mean baseline IOP was 21.5±5 mmHg, and the mean change in IOP from baseline in the treated eye at one year was −4.67±3.40 mmHg.
Higher baseline IOP was highly correlated with greater absolute IOP decrease.
Prostaglandin analogue use at baseline was shown to be associated with a statistically decreased IOP-lowering response following SLT when corrected for baseline IOP.
No significant differences in IOP response were found when comparing groups stratified for age, angle pigmentation, phakic status, gender, or diagnosis.
Discussion.
The results of this study confirm the finding that higher baseline IOP is a predictor of greater IOP response following SLT, and that pretreatment with prostaglandin analogue therapy is associated with a decreased IOP-lowering response following SLT.
The study is limited by the small number of eyes with data available for complete case analysis.
American Psychological Association (APA)
Bruen, Robin& Lesk, Mark R.& Harasymowycz, Paul. 2012. Baseline Factors Predictive of SLT Response : A Prospective Study. Journal of Ophthalmology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-487634
Modern Language Association (MLA)
Bruen, Robin…[et al.]. Baseline Factors Predictive of SLT Response : A Prospective Study. Journal of Ophthalmology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-487634
American Medical Association (AMA)
Bruen, Robin& Lesk, Mark R.& Harasymowycz, Paul. Baseline Factors Predictive of SLT Response : A Prospective Study. Journal of Ophthalmology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-487634
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487634