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Impact of Changes in Perinatal Care on Neonatal Respiratory Outcome and Survival of Preterm Newborns : An Overview of 15 Years
Joint Authors
Guimarães, Hercília
Flor-de-Lima, Filipa
Rocha, Gustavo
Source
Critical Care Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-20
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Survival and outcomes for preterm infants with respiratory distress syndrome (RDS) have improved over the past 30 years.
We conducted a study to assess the changes in perinatal care and delivery room management and their impact on respiratory outcome of very low birth weight newborns, over the last 15 years.
A comparison between two epochs was performed, the periods before and after 2005, when early nasal continuous positive airway pressure (NCPAP) and Intubation-SURfactant-Extubation (INSURE) were introduced in our center.
Three hundred ninety-five clinical records were assessed, 198 (50.1%) females, gestational age 29.1 weeks (22–36), and birth weight 1130 g (360–1498).
RDS was diagnosed in 247 (62.5%) newborns and exogenous surfactant was administered to 217 (54.9%).
Thirty-three (8.4%) developed bronchopulmonary dysplasia (BPD), and 92 (23%) were deceased.
With the introduction of early NCPAP and INSURE, there was a decrease on the endotracheal intubation need and invasive ventilation (P<0.0001), oxygen therapy (P=0.002), and mortality (P<0.0001).
The multivariate model revealed a nonsignificant reduction in BPD between the two epochs (OR=0.86; 95% CI 0.074–9.95; P=0.9).
The changes in perinatal care over the last 15 years were associated to an improvement of respiratory outcome and survival, despite a nonsignificant decrease in BPD rate.
American Psychological Association (APA)
Flor-de-Lima, Filipa& Rocha, Gustavo& Guimarães, Hercília. 2012. Impact of Changes in Perinatal Care on Neonatal Respiratory Outcome and Survival of Preterm Newborns : An Overview of 15 Years. Critical Care Research and Practice،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-487667
Modern Language Association (MLA)
Flor-de-Lima, Filipa…[et al.]. Impact of Changes in Perinatal Care on Neonatal Respiratory Outcome and Survival of Preterm Newborns : An Overview of 15 Years. Critical Care Research and Practice No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-487667
American Medical Association (AMA)
Flor-de-Lima, Filipa& Rocha, Gustavo& Guimarães, Hercília. Impact of Changes in Perinatal Care on Neonatal Respiratory Outcome and Survival of Preterm Newborns : An Overview of 15 Years. Critical Care Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-487667
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487667