Current Methods in the Molecular Typing of Mycobacterium tuberculosis and Other Mycobacteria
Joint Authors
van Ingen, Jakko
Jagielski, Tomasz
Dziadek, Jaroslaw
Rastogi, Nalin
Bielecki, Jacek
Mazur, Paweł K.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-21, 21 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-05
Country of Publication
Egypt
No. of Pages
21
Main Subjects
Abstract EN
In the epidemiology of tuberculosis (TB) and nontuberculous mycobacterial (NTM) diseases, as in all infectious diseases, the key issue is to define the source of infection and to disclose its routes of transmission and dissemination in the environment.
For this to be accomplished, the ability of discerning and tracking individual Mycobacterium strains is of critical importance.
Molecular typing methods have greatly improved our understanding of the biology of mycobacteria and provide powerful tools to combat the diseases caused by these pathogens.
The utility of various typing methods depends on the Mycobacterium species under investigation as well as on the research question.
For tuberculosis, different methods have different roles in phylogenetic analyses and person-to-person transmission studies.
In NTM diseases, most investigations involve the search for environmental sources or phylogenetic relationships.
Here, too, the type of setting determines which methodology is most suitable.
Within this review, we summarize currently available molecular methods for strain typing of M.
tuberculosis and some NTM species, most commonly associated with human disease.
For the various methods, technical practicalities as well as discriminatory power and accomplishments are reviewed.
American Psychological Association (APA)
Jagielski, Tomasz& van Ingen, Jakko& Rastogi, Nalin& Dziadek, Jaroslaw& Mazur, Paweł K.& Bielecki, Jacek. 2014. Current Methods in the Molecular Typing of Mycobacterium tuberculosis and Other Mycobacteria. BioMed Research International،Vol. 2014, no. 2014, pp.1-21.
https://search.emarefa.net/detail/BIM-487812
Modern Language Association (MLA)
Jagielski, Tomasz…[et al.]. Current Methods in the Molecular Typing of Mycobacterium tuberculosis and Other Mycobacteria. BioMed Research International No. 2014 (2014), pp.1-21.
https://search.emarefa.net/detail/BIM-487812
American Medical Association (AMA)
Jagielski, Tomasz& van Ingen, Jakko& Rastogi, Nalin& Dziadek, Jaroslaw& Mazur, Paweł K.& Bielecki, Jacek. Current Methods in the Molecular Typing of Mycobacterium tuberculosis and Other Mycobacteria. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-21.
https://search.emarefa.net/detail/BIM-487812
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487812