Preparation of DNAGold Nanoparticle Encapsulated in Calcium Phosphate
Joint Authors
Ito, Tomoko
Ibe, Koyuki
Otsuka, Makoto
Ohshima, Hiroyuki
Uchino, Tomohiro
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Biocompatible DNA/gold nanoparticle complex with a protective calcium phosphate (CaP) coating was prepared by incubating DNA/gold nanoparticle complex coated by hyaluronic acid in SBF (simulated body fluid) with a Ca concentration above 2 mM.
The CaP-coated DNA complex was revealed to have high compatibility with cells and resistance against enzymatic degradation.
By immersion in acetate buffer (pH 4.5), the CaP capsule released the contained DNA complex.
This CaP capsule including a DNA complex is promising as a sustained-release system of DNA complexes for gene therapy.
American Psychological Association (APA)
Ito, Tomoko& Ibe, Koyuki& Uchino, Tomohiro& Ohshima, Hiroyuki& Otsuka, Makoto. 2011. Preparation of DNAGold Nanoparticle Encapsulated in Calcium Phosphate. Journal of Drug Delivery،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-487957
Modern Language Association (MLA)
Ito, Tomoko…[et al.]. Preparation of DNAGold Nanoparticle Encapsulated in Calcium Phosphate. Journal of Drug Delivery No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-487957
American Medical Association (AMA)
Ito, Tomoko& Ibe, Koyuki& Uchino, Tomohiro& Ohshima, Hiroyuki& Otsuka, Makoto. Preparation of DNAGold Nanoparticle Encapsulated in Calcium Phosphate. Journal of Drug Delivery. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-487957
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487957
