Effect of Modified Formula Radix Hedysari on the Amplification Effect during Peripheral Nerve Regeneration
Joint Authors
Kou, Yu Hui
Zhang, Pei Xun
Wang, Zhi Yong
Han, Na
Yin, Xiao Feng
Jiang, Bao Guo
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Many studies have demonstrated a compensatory amplification phenomenon during nerve regeneration.
When a relatively fine nerve is used as a donor to connect to a distal nerve after transection, the donor nerve regenerates more collaterals than its own fibers, which extend to the distal stump, grow into distal endoneurial tubes, and finally reach and dominate the target organs.
This is known as the amplification phenomenon.
In this study, we investigated the amplification phenomenon in rats treated with Modified Formula Radix Hedysari (MFRH) as adjuvant therapy for 12 weeks.
The rats were divided into three groups at random (six animals in each group).
In the model group and the treatment group, the proximal common peroneal nerve was used as a donor nerve to connect to the distal tibial nerve.
Rats in the normal group did not undergo surgery.
After surgery, the treatment group was administered MFRH as systemic therapy, while the model group and the normal group were not given treatment.
The results demonstrated that the nerve conduction velocity, the fiber diameter, the axon diameter, the number of regenerating nerve fibers, and the amplification ratio were better in the treatment group than in the model group, suggesting that MFRH promoted the nerve amplification effect.
American Psychological Association (APA)
Wang, Zhi Yong& Zhang, Pei Xun& Han, Na& Kou, Yu Hui& Yin, Xiao Feng& Jiang, Bao Guo. 2013. Effect of Modified Formula Radix Hedysari on the Amplification Effect during Peripheral Nerve Regeneration. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-487986
Modern Language Association (MLA)
Wang, Zhi Yong…[et al.]. Effect of Modified Formula Radix Hedysari on the Amplification Effect during Peripheral Nerve Regeneration. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-487986
American Medical Association (AMA)
Wang, Zhi Yong& Zhang, Pei Xun& Han, Na& Kou, Yu Hui& Yin, Xiao Feng& Jiang, Bao Guo. Effect of Modified Formula Radix Hedysari on the Amplification Effect during Peripheral Nerve Regeneration. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-487986
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-487986