A Clinical Analysis of Risk Factors for Interstitial Lung Disease in Patients with Idiopathic Inflammatory Myopathy
Joint Authors
Xie, Qibing
Cen, Xiaomin
Yin, Geng
Yang, Min
Zuo, Chuan
Source
Clinical and Developmental Immunology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Interstitial lung disease (ILD) is a common and severe complication of idiopathic inflammatory myopathies (IIM).
The aim of our study was to identify risk factors for ILD by evaluating both clinical and biochemical features in IIM patients with or without ILD.
From January 2008 to December 2011, medical records of 134 IIM patients in our rheumatology unit were reviewed.
The patients were divided into ILD group (83 patients) and non-ILD group (51 patients).
The clinical features and laboratory findings were compared.
The univariable analyses indicated that arthritis/arthralgia (54.2% versus 17.6%, P<0.05), Mechanic’s hand (16.9% versus 2.0%, P<0.05), Raynaud’s phenomenon (36.1% versus 2.0%, P<0.05), heliotrope rash (44.6% versus 19.6%, P<0.05), fever (43.4% versus 21.6%, P<0.05), elevated ESR (60.2% versus 35.3%, P<0.05), elevated CRP (55.4% versus 31.4%, P<0.05), or anti-Jo-1 antibody (20.5% versus 5.9%, P<0.05) were risk factors for developing ILD in IIM.
Multivariable unconditional logistic regression analysis that showed arthritis/arthralgia (OR 7.1, 95% CI 2.8–18.1), Raynaud’s phenomenon (OR 29.1, 95% CI 3.6–233.7), and amyopathic dermatomyositis (ADM) (OR 20.2, 95% CI 2.4–171.2) were the independent risk factors for developing ILD in IIM.
American Psychological Association (APA)
Cen, Xiaomin& Zuo, Chuan& Yang, Min& Yin, Geng& Xie, Qibing. 2013. A Clinical Analysis of Risk Factors for Interstitial Lung Disease in Patients with Idiopathic Inflammatory Myopathy. Clinical and Developmental Immunology،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-488047
Modern Language Association (MLA)
Cen, Xiaomin…[et al.]. A Clinical Analysis of Risk Factors for Interstitial Lung Disease in Patients with Idiopathic Inflammatory Myopathy. Clinical and Developmental Immunology No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-488047
American Medical Association (AMA)
Cen, Xiaomin& Zuo, Chuan& Yang, Min& Yin, Geng& Xie, Qibing. A Clinical Analysis of Risk Factors for Interstitial Lung Disease in Patients with Idiopathic Inflammatory Myopathy. Clinical and Developmental Immunology. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-488047
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488047