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Parathyroid Carcinoma : The Importance of High Clinical Suspicion for a Correct Management
Joint Authors
Tufodandria, Giovanni
Marini, Pierluigi
Assenza, Marco
Paganelli, Livio
Liotta, Gianluca
Barreca, Marco
Ricci, Gabriele
Serao, Angelo
Source
International Journal of Surgical Oncology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-19
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Parathyroid carcinoma is an infrequent clinical entity whose diagnosis is very challenge.
Indeed a pre-operative or intraoperative diagnosis of parathyroid carcinoma is reported in less than half cases described in the literature.
Patients and Methods.
A systematic review of pathological reports of our secondary referral hospital was done.
From 2003 to 2011 one hundred and forty-four patients were operated for hyperparathyroidism.
One patient with atypical adenoma and three patients with parathyroid carcinoma were included in this paper.
Results.
An en bloc resection of the tumor was performed in three patients.
Two of this patients with diagnosis of parathyroid carcinoma are alive with no evidence of recurrence or metastasis, respectively, 48 and 60 months after the operation; one patient with diagnosis of atypical adenoma died for other disease 16 months after the operation.
In the last patient a simple parathyroidectomy was performed.
After that histology revealed the diagnosis of parathyroid carcinoma the patient underwent reoperation for left hemithyroidectomy and central compartment lymph node clearance.
After 30 months a lung lobectomy was done due to metastasis.
Conclusion.
Parathyroid carcinoma should be considered in the differential diagnosis of PTH-dependent hypercalcemia because optional outcomes are associated with complete resection of the tumor at the time of initial operation.
American Psychological Association (APA)
Ricci, Gabriele& Assenza, Marco& Barreca, Marco& Liotta, Gianluca& Paganelli, Livio& Serao, Angelo…[et al.]. 2012. Parathyroid Carcinoma : The Importance of High Clinical Suspicion for a Correct Management. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-488095
Modern Language Association (MLA)
Ricci, Gabriele…[et al.]. Parathyroid Carcinoma : The Importance of High Clinical Suspicion for a Correct Management. International Journal of Surgical Oncology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-488095
American Medical Association (AMA)
Ricci, Gabriele& Assenza, Marco& Barreca, Marco& Liotta, Gianluca& Paganelli, Livio& Serao, Angelo…[et al.]. Parathyroid Carcinoma : The Importance of High Clinical Suspicion for a Correct Management. International Journal of Surgical Oncology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-488095
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488095