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Protective Effect of Theaflavin on Erythrocytes Subjected to In Vitro Oxidative Stress
Joint Authors
Kesharwani, Rajesh Kumar
Misra, Krishna
Rizvi, Syed Ibrahim
Fatima, Mahejabeen
Source
Biochemistry Research International
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Antioxidant and free radical scavenging effect of black tea theaflavins has been shown in many epidemiological studies.
In the present work we report the protective mechanism of tea theaflavins on biomarkers of oxidative stress, which are elevated during stress conditions.
We hereby report the in vitro effect of theaflavins on erythrocyte malondialdehyde (MDA), intracellular reduced glutathione (GSH), and plasma membrane redox system (PMRS) of rats.
The effect of theaflavin on PMRS has also been validated through an in silico docking simulation study using Molegro Virtual Docker (MVD).
We report that theaflavins show significant protection to erythrocyte against oxidative stress induced by tert-butyl hydroperoxide (t-BHP).
The findings suggest a possible protective role of theaflavins as antioxidant.
American Psychological Association (APA)
Fatima, Mahejabeen& Kesharwani, Rajesh Kumar& Misra, Krishna& Rizvi, Syed Ibrahim. 2013. Protective Effect of Theaflavin on Erythrocytes Subjected to In Vitro Oxidative Stress. Biochemistry Research International،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-488178
Modern Language Association (MLA)
Fatima, Mahejabeen…[et al.]. Protective Effect of Theaflavin on Erythrocytes Subjected to In Vitro Oxidative Stress. Biochemistry Research International No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-488178
American Medical Association (AMA)
Fatima, Mahejabeen& Kesharwani, Rajesh Kumar& Misra, Krishna& Rizvi, Syed Ibrahim. Protective Effect of Theaflavin on Erythrocytes Subjected to In Vitro Oxidative Stress. Biochemistry Research International. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-488178
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488178