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Application of 2-Trichloromethylbenzimidazole in Analytical Chemistry : A Highly Selective Chromogenic Reagent for Thin-Layer Chromatography and Some Other Analytical Uses
Joint Authors
Konopski, Leszek
Kiełczewska, Anna
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-04
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
2-Trichloromethylbenzimidazole (TCMB) was used as a chromogenic reagent in organic or inorganic analysis, mainly in thin-layer chromatography (TLC).
In reactions of TCMB with some heteroaromatic nitrogen containing compounds, such as azines, azoles and benzazoles, a formation of high colored products occurred.
For azines, the chromogenic reaction was highly regioselective, since the both adjacent α-positions versus the nitrogen atom(s) must not be substituted.
A TLC method of detection was developed.
Thirty azines, azoles, and benzazoles were detected at the detection limit 10 ng to 1 μg.
This method was also applied for detection of heteroaromatic pesticides, and the attempts to construct active and passive dosimeters for nicotine were made.
In a prechromatographic reaction of aromatic o-diamines with methyl trichloroacetimidate, TCMB or its derivatives were formed in situ.
Followed by TLC and visualization in pyridine vapors, this procedure was applied for detection of o-phenylenediamine derivatives.
The reaction product of TCMB and pyridine (LI Complex) was identified and fully characterized.
Two different reaction mechanisms: with electron deficient basic heteroaromatic compounds, like pyridine, and with more acidic compounds, for example, pyrrole, were discussed.
In aqueous solutions, the LI Complex may be also used as a new indicator for complexometric, adsorption and acid-base titration of inorganic compounds.
American Psychological Association (APA)
Konopski, Leszek& Kiełczewska, Anna. 2012. Application of 2-Trichloromethylbenzimidazole in Analytical Chemistry : A Highly Selective Chromogenic Reagent for Thin-Layer Chromatography and Some Other Analytical Uses. Journal of Analytical Methods in Chemistry،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-488193
Modern Language Association (MLA)
Konopski, Leszek& Kiełczewska, Anna. Application of 2-Trichloromethylbenzimidazole in Analytical Chemistry : A Highly Selective Chromogenic Reagent for Thin-Layer Chromatography and Some Other Analytical Uses. Journal of Analytical Methods in Chemistry No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-488193
American Medical Association (AMA)
Konopski, Leszek& Kiełczewska, Anna. Application of 2-Trichloromethylbenzimidazole in Analytical Chemistry : A Highly Selective Chromogenic Reagent for Thin-Layer Chromatography and Some Other Analytical Uses. Journal of Analytical Methods in Chemistry. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-488193
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488193