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Sedation and Analgesia in Intensive Care : A Comparison of Fentanyl and Remifentanil
Joint Authors
Cevik, F.
Macit, C.
Clark, P. M.
Celik, M.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-02
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Optimal sedation and analgesia are of key importance in intensive care.
The aim of this study was to assess the quality of sedoanalgesia and outcome parameters in regimens containing midazolam and either fentanyl or remifentanil.
A prospective, randomized, open-label, controlled trial was carried out in the ICU unit of a large teaching hospital in Istanbul over a 9-month period.
Thirty-four patients were randomly allocated to receive either a remifentanil-midazolam regimen (R group, n=17) or a fentanyl-midazolam regimen (F group, n=17).
A strong correlation between Riker Sedation-Agitation Scale (SAS) and Ramsey Scale (RS) measurements was observed.
Comparatively, remifentanil provided significantly more potent and rapid analgesia based on Behavioral-Physiological Scale (BPS) measurements and a statistically nonsignificantly shorter time to discharge.
On the other hand, remifentanil also caused a significantly sharper fall in heart rate within the first six hours of treatment.
American Psychological Association (APA)
Cevik, F.& Celik, M.& Clark, P. M.& Macit, C.. 2011. Sedation and Analgesia in Intensive Care : A Comparison of Fentanyl and Remifentanil. Pain Research and Treatment،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-488210
Modern Language Association (MLA)
Cevik, F.…[et al.]. Sedation and Analgesia in Intensive Care : A Comparison of Fentanyl and Remifentanil. Pain Research and Treatment No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-488210
American Medical Association (AMA)
Cevik, F.& Celik, M.& Clark, P. M.& Macit, C.. Sedation and Analgesia in Intensive Care : A Comparison of Fentanyl and Remifentanil. Pain Research and Treatment. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-488210
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488210