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Prognostic Factors in Patients with Multiple Recurrences of Well-Differentiated Thyroid Carcinoma
Joint Authors
Theriault, Jenna
Payne, Richard J.
Holler, Theresa
Freeman, Jeremy L.
Clark, Jonathan
Eski, Spiro
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-10-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
Patients with multiple recurrences of well-differentiated thyroid carcinoma (WDTC) have markedly reduced overall survival when compared with those who have ≤1 recurrence of their disease.
The purpose of this investigation is to identify prognostic factors for mortality in this subgroup.
Methods.
Patients with multiple recurrences of WDTC were retrospectively identified from the thyroid cancer database at Mount Sinai Hospital, Toronto (1963–2000).
Data on patient, tumor, and recurrence characteristics were collected, and each patient was given aMACIS score.
Results.
A total of 31 patients were identified (11 male, 20 female; 16–83 years).
Using univariate analysis, age >45, stage III/IV disease, distant metastasis, vascular invasion, MACIS score >6, and time to recurrence of <12 months were found to be significant predictors for mortality in this subgroup.
Conclusions.
Patients with multiple recurrences of WDTC follow a distinct clinical course, marked with multiple treatment failures and a substantial risk of mortality.
American Psychological Association (APA)
Holler, Theresa& Theriault, Jenna& Payne, Richard J.& Clark, Jonathan& Eski, Spiro& Freeman, Jeremy L.. 2009. Prognostic Factors in Patients with Multiple Recurrences of Well-Differentiated Thyroid Carcinoma. Journal of Oncology،Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-488213
Modern Language Association (MLA)
Holler, Theresa…[et al.]. Prognostic Factors in Patients with Multiple Recurrences of Well-Differentiated Thyroid Carcinoma. Journal of Oncology No. 2009 (2009), pp.1-6.
https://search.emarefa.net/detail/BIM-488213
American Medical Association (AMA)
Holler, Theresa& Theriault, Jenna& Payne, Richard J.& Clark, Jonathan& Eski, Spiro& Freeman, Jeremy L.. Prognostic Factors in Patients with Multiple Recurrences of Well-Differentiated Thyroid Carcinoma. Journal of Oncology. 2009. Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-488213
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488213