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Review : Magnetic Resonance Spectroscopy Studies of Pediatric Major Depressive Disorder
Joint Authors
Kim, Namkug
DelMastro, Kristen K.
Sung, Young-Hoon
Jeong, Eun-Kee
Renshaw, Perry F.
Hellem, Tracy L.
Shi, Xianfeng
Kondo, Douglas G.
Source
Depression Research and Treatment
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-10-04
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Introduction.
This paper focuses on the application of Magnetic Resonance Spectroscopy (MRS) to the study of Major Depressive Disorder (MDD) in children and adolescents.
Method.
A literature search using the National Institutes of Health's PubMed database was conducted to identify indexed peer-reviewed MRS studies in pediatric patients with MDD.
Results.
The literature search yielded 18 articles reporting original MRS data in pediatric MDD.
Neurochemical alterations in Choline, Glutamate, and N-Acetyl Aspartate are associated with pediatric MDD, suggesting pathophysiologic continuity with adult MDD.
Conclusions.
The MRS literature in pediatric MDD is modest but growing.
In studies that are methodologically comparable, the results have been consistent.
Because it offers a noninvasive and repeatable measurement of relevant in vivo brain chemistry, MRS has the potential to provide insights into the pathophysiology of MDD as well as the mediators and moderators of treatment response.
American Psychological Association (APA)
Kondo, Douglas G.& Hellem, Tracy L.& Sung, Young-Hoon& Kim, Namkug& Jeong, Eun-Kee& DelMastro, Kristen K.…[et al.]. 2010. Review : Magnetic Resonance Spectroscopy Studies of Pediatric Major Depressive Disorder. Depression Research and Treatment،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-488220
Modern Language Association (MLA)
Kondo, Douglas G.…[et al.]. Review : Magnetic Resonance Spectroscopy Studies of Pediatric Major Depressive Disorder. Depression Research and Treatment No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-488220
American Medical Association (AMA)
Kondo, Douglas G.& Hellem, Tracy L.& Sung, Young-Hoon& Kim, Namkug& Jeong, Eun-Kee& DelMastro, Kristen K.…[et al.]. Review : Magnetic Resonance Spectroscopy Studies of Pediatric Major Depressive Disorder. Depression Research and Treatment. 2010. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-488220
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488220