Development of a Stereotaxic Device for Low Impact Implantation of Neural Constructs or Pieces of Neural Tissues into the Mammalian Brain
Joint Authors
Jozwiak, Andrzej
Gates, Monte A.
Yang, Ying
Liu, Yiwen
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-23
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Implanting pieces of tissue or scaffolding material into the mammalian central nervous system (CNS) is wrought with difficulties surrounding the size of tools needed to conduct such implants and the ability to maintain the orientation and integrity of the constructs during and after their transplantation.
Here, novel technology has been developed that allows for the implantation of neural constructs or intact pieces of neural tissue into the CNS with low trauma.
By “laying out” (instead of forcibly expelling) the implantable material from a thin walled glass capillary, this technology has the potential to enhance neural transplantation procedures by reducing trauma to the host brain during implantation and allowing for the implantation of engineered/dissected tissues or constructs in such a way that their orientation and integrity are maintained in the host.
Such technology may be useful for treating various CNS disorders which require the reestablishment of point-to-point contacts (e.g., Parkinson’s disease) across the adult CNS, an environment which is not normally permissive to axonal growth.
American Psychological Association (APA)
Jozwiak, Andrzej& Liu, Yiwen& Yang, Ying& Gates, Monte A.. 2014. Development of a Stereotaxic Device for Low Impact Implantation of Neural Constructs or Pieces of Neural Tissues into the Mammalian Brain. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-488291
Modern Language Association (MLA)
Jozwiak, Andrzej…[et al.]. Development of a Stereotaxic Device for Low Impact Implantation of Neural Constructs or Pieces of Neural Tissues into the Mammalian Brain. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-488291
American Medical Association (AMA)
Jozwiak, Andrzej& Liu, Yiwen& Yang, Ying& Gates, Monte A.. Development of a Stereotaxic Device for Low Impact Implantation of Neural Constructs or Pieces of Neural Tissues into the Mammalian Brain. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-488291
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488291