Manipulation of Polyhydroxybutyrate Properties through Blending with Ethyl-Cellulose for a Composite Biomaterial
Joint Authors
Foster, Leslie John Ray
Russell, Robert A.
Chan, Rodman T. H.
Garvey, Christopher J.
Holden, Peter J.
Marçal, Helder
Source
International Journal of Polymer Science
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Polyhydroxybutyrate (PHB) is widely used as a biomaterial in medical and tissue-engineering applications, a relatively high crystallinity limits its application.
Blending PHB with ethyl-cellulose (EtC) was readily achieved to reduce PHB crystallinity and promote its degradation under physiological conditions without undue influence on biocompatibility.
Material strength of composite films remained unchanged at 6.5 ± 0.6 MPa with 40% (w/w) EtC loadings.
Phase separation between the two biopolymers was determined with PHB crystallinity decreasing from 63% to 47% for films with the same loading.
This reduction in crystallinity supported an increase in the degradation rates of composite films from 0.39 to 0.81% wk−1 for PHB and its composite, respectively.
No significant change in morphology and proliferation of olfactory ensheathing cells were observed with the composites despite significant increases in average surface roughness (Ra) of the films from 2.90 to 3.65 μm for PHB and blends with 80% (w/w) EtC, respectively.
American Psychological Association (APA)
Chan, Rodman T. H.& Garvey, Christopher J.& Marçal, Helder& Russell, Robert A.& Holden, Peter J.& Foster, Leslie John Ray. 2011. Manipulation of Polyhydroxybutyrate Properties through Blending with Ethyl-Cellulose for a Composite Biomaterial. International Journal of Polymer Science،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-488324
Modern Language Association (MLA)
Chan, Rodman T. H.…[et al.]. Manipulation of Polyhydroxybutyrate Properties through Blending with Ethyl-Cellulose for a Composite Biomaterial. International Journal of Polymer Science No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-488324
American Medical Association (AMA)
Chan, Rodman T. H.& Garvey, Christopher J.& Marçal, Helder& Russell, Robert A.& Holden, Peter J.& Foster, Leslie John Ray. Manipulation of Polyhydroxybutyrate Properties through Blending with Ethyl-Cellulose for a Composite Biomaterial. International Journal of Polymer Science. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-488324
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488324