Good Clinical Response in a Rare Aggressive Hematopoietic Neoplasm : Plasmacytoid Dendritic Cell Leukemia with No Cutaneous Lesions Responding to 4 Donor Lymphocyte Infusions Following Transplant
Joint Authors
Kansal, Rina
Wong, Matthew
Lill, Michael
Lopategui, Jean
Steinberg, Amir
Lim, Stephen
Lopez, Angela
Source
Case Reports in Transplantation
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-08
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a rare and aggressive malignancy that usually presents with diffuse cutaneous lesions.
While a favorable response to therapy occurs in a majority of cases, a sustained long-term response is uncommon.
Most patients subsequently relapse within a year.
In the following report, we present the case of a 41-year-old woman who has not displayed many of the clinical features traditionally associated with BPDCN.
The patient received sporadic chemotherapy treatment over the course of 2 years, before undergoing an allogeneic stem cell transplant.
Although she ultimately relapsed following her transplant, her disease has repeatedly returned into remission after donor lymphocyte infusion (DLI).
Currently, the patient is in remission following her fourth DLI.
We believe that allogeneic transplantation should be considered as front-line therapy for the treatment of this rare malignancy.
American Psychological Association (APA)
Steinberg, Amir& Kansal, Rina& Wong, Matthew& Lopez, Angela& Lim, Stephen& Lopategui, Jean…[et al.]. 2011. Good Clinical Response in a Rare Aggressive Hematopoietic Neoplasm : Plasmacytoid Dendritic Cell Leukemia with No Cutaneous Lesions Responding to 4 Donor Lymphocyte Infusions Following Transplant. Case Reports in Transplantation،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-488370
Modern Language Association (MLA)
Steinberg, Amir…[et al.]. Good Clinical Response in a Rare Aggressive Hematopoietic Neoplasm : Plasmacytoid Dendritic Cell Leukemia with No Cutaneous Lesions Responding to 4 Donor Lymphocyte Infusions Following Transplant. Case Reports in Transplantation No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-488370
American Medical Association (AMA)
Steinberg, Amir& Kansal, Rina& Wong, Matthew& Lopez, Angela& Lim, Stephen& Lopategui, Jean…[et al.]. Good Clinical Response in a Rare Aggressive Hematopoietic Neoplasm : Plasmacytoid Dendritic Cell Leukemia with No Cutaneous Lesions Responding to 4 Donor Lymphocyte Infusions Following Transplant. Case Reports in Transplantation. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-488370
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488370