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Molecular and Clinical Aspects of Targeting the VEGF Pathway in Tumors
Joint Authors
Sullivan, Laura A.
Korpanty, Grzegorz
Smyth, Elizabeth
Brekken, Rolf A.
Carney, Desmond N.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-10
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Tumor angiogenesis is a complex process resulting from many signals from the tumor microenvironment.
From preclinical animal models to clinical trials and practice, targeting tumors with antiangiogenic therapy remains an exciting area of study.
Although many scientific advances have been achieved, leading to the development and clinical use of antiangiogenic drugs such as bevacizumab, sorafenib, and sunitinib, these therapies fall short of their anticipated benefits and leave many questions unanswered.
Continued research into the complex signaling cascades that promote tumor angiogenesis may yield new targets or improve upon current therapies.
In addition, the development of reliable tools to track tumor responses to antiangiogenic therapy will enable a better understanding of current therapeutic efficacy and may elucidate mechanisms to predict patient response to therapy.
American Psychological Association (APA)
Korpanty, Grzegorz& Sullivan, Laura A.& Smyth, Elizabeth& Carney, Desmond N.& Brekken, Rolf A.. 2010. Molecular and Clinical Aspects of Targeting the VEGF Pathway in Tumors. Journal of Oncology،Vol. 2010, no. 2010, pp.1-12.
https://search.emarefa.net/detail/BIM-488412
Modern Language Association (MLA)
Korpanty, Grzegorz…[et al.]. Molecular and Clinical Aspects of Targeting the VEGF Pathway in Tumors. Journal of Oncology No. 2010 (2010), pp.1-12.
https://search.emarefa.net/detail/BIM-488412
American Medical Association (AMA)
Korpanty, Grzegorz& Sullivan, Laura A.& Smyth, Elizabeth& Carney, Desmond N.& Brekken, Rolf A.. Molecular and Clinical Aspects of Targeting the VEGF Pathway in Tumors. Journal of Oncology. 2010. Vol. 2010, no. 2010, pp.1-12.
https://search.emarefa.net/detail/BIM-488412
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488412