Retrobulbar Hemodynamic Effects of Nipradilol in Normal and Normal-Tension Glaucoma Eyes
Joint Authors
Sugimoto, Masahiko
Ido, Masashi
Ito, Kunio
Uji, Yukitaka
Osawa, Syunsuke
Sasoh, Mikio
Furuta, Motoyasu
Fukukita, Mitsushi
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To investigate the effects of nipradilol on retrobulbar hemodynamics.
Methods.
We investigated normal and normal-tension glaucoma (NTG) eyes.
Topical nipradilol (one eye) and placebo eye drops (fellow eye) were instilled for 1 week in volunteers.
Nipradilol was also instilled in NTG patients.
Ultrasound color Doppler imaging for the posterior vessels was performed before, 2 hr, 1 week (for normal), and at 4 weeks (for NTG).
Results.
In normal eyes, there were significant decreases in the resistance index (RI) for the temporal short posterior ciliary arteries (PCA) at 2 hr and for the ophthalmic arteries at 1 week.
There were no significant changes in the placebo-treated eyes.
In the NTG eyes, there was a significant decrease in the RI for the central retinal artery, nasal, and temporal PCA at 2 hr and 4 weeks.
Conclusion.
Short-term observations found that nipradilol increased the ocular blood flow in normal and NTG eyes.
American Psychological Association (APA)
Fukukita, Mitsushi& Ido, Masashi& Osawa, Syunsuke& Sasoh, Mikio& Furuta, Motoyasu& Ito, Kunio…[et al.]. 2011. Retrobulbar Hemodynamic Effects of Nipradilol in Normal and Normal-Tension Glaucoma Eyes. Journal of Ophthalmology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-488486
Modern Language Association (MLA)
Fukukita, Mitsushi…[et al.]. Retrobulbar Hemodynamic Effects of Nipradilol in Normal and Normal-Tension Glaucoma Eyes. Journal of Ophthalmology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-488486
American Medical Association (AMA)
Fukukita, Mitsushi& Ido, Masashi& Osawa, Syunsuke& Sasoh, Mikio& Furuta, Motoyasu& Ito, Kunio…[et al.]. Retrobulbar Hemodynamic Effects of Nipradilol in Normal and Normal-Tension Glaucoma Eyes. Journal of Ophthalmology. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-488486
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488486