Cardiorenal Syndromes and Sepsis
Joint Authors
De Gaudio, A. R.
Villa, G.
Chelazzi, C.
Source
International Journal of Nephrology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The cardiorenal syndrome is a clinical and pathophysiological entity defined as the concomitant presence of renal and cardiovascular dysfunction.
In patients with severe sepsis and septic shock, acute cardiovascular, and renal derangements are common, that is, the septic cardiorenal syndrome.
The aim of this paper is to describe the pathophysiology and clinical features of septic cardiorenal syndrome in light of the actual clinical and experimental evidence.
In particular, the importance of systemic and intrarenal endothelial dysfunction, alterations of kidney perfusion, and myocardial function, organ “crosstalk” and ubiquitous inflammatory injury have been extensively reviewed in light of their role in cardiorenal syndrome etiology.
Treatment includes early and targeted optimization of hemodynamics to reverse systemic hypotension and restore urinary output.
In case of persistent renal impairment, renal replacement therapy may be used to remove cytokines and restore renal function.
American Psychological Association (APA)
Chelazzi, C.& Villa, G.& De Gaudio, A. R.. 2011. Cardiorenal Syndromes and Sepsis. International Journal of Nephrology،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-488493
Modern Language Association (MLA)
Chelazzi, C.…[et al.]. Cardiorenal Syndromes and Sepsis. International Journal of Nephrology No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-488493
American Medical Association (AMA)
Chelazzi, C.& Villa, G.& De Gaudio, A. R.. Cardiorenal Syndromes and Sepsis. International Journal of Nephrology. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-488493
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488493