Metabolic Syndrome, Chronic Kidney, and Cardiovascular Diseases : Role of Adipokines
Joint Authors
Rodia, Giuseppe
Canale, Maria Paola
Lauro, Davide
Di Daniele, Nicola
Scuteri, Angelo
Tesauro, Manfredi
Cardillo, Carmine
Source
Cardiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-07
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Obesity is a chronic disease, whose incidence is alarmingly growing.
It is associated with metabolic abnormalities and cardiovascular complications.
These complications are clustered in the metabolic syndrome (MetS) leading to high cardiovascular morbidity and mortality.
Obesity predisposes to diabetic nephropathy, hypertensive nephrosclerosis, and focal and segmental glomerular sclerosis and represents an independent risk factor for the development and progression of chronic kidney disease (CKD).
Albuminuria is a major risk factor for cardiovascular diseases (CVDs).
Microalbuminuria has been described as early manifestation of MetS-associated kidney damage and diabetic nephropathy.
Obesity and MetS affect renal physiology and metabolism through mechanisms which include altered levels of adipokines such as leptin and adiponectin, oxidative stress, and inflammation.
Secretory products of adipose tissue also deeply and negatively influence endothelial function.
A better understanding of these interactions will help in designing more effective treatments aimed to protect both renal and cardiovascular systems.
American Psychological Association (APA)
Tesauro, Manfredi& Canale, Maria Paola& Rodia, Giuseppe& Di Daniele, Nicola& Lauro, Davide& Scuteri, Angelo…[et al.]. 2011. Metabolic Syndrome, Chronic Kidney, and Cardiovascular Diseases : Role of Adipokines. Cardiology Research and Practice،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-488514
Modern Language Association (MLA)
Tesauro, Manfredi…[et al.]. Metabolic Syndrome, Chronic Kidney, and Cardiovascular Diseases : Role of Adipokines. Cardiology Research and Practice No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-488514
American Medical Association (AMA)
Tesauro, Manfredi& Canale, Maria Paola& Rodia, Giuseppe& Di Daniele, Nicola& Lauro, Davide& Scuteri, Angelo…[et al.]. Metabolic Syndrome, Chronic Kidney, and Cardiovascular Diseases : Role of Adipokines. Cardiology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-488514
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488514