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Impact of Diabetes on Cardiovascular Disease : An Update
Joint Authors
Negrato, Carlos Antonio
Gomes, Marilia de Brito
Palma, Catia C. Sousa
Matheus, Alessandra Saldanha de Mattos
Cobas, Roberta Arnoldi
Tannus, Lucianne Righeti Monteiro
Source
International Journal of Hypertension
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-04
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Cardiovascular diseases are the most prevalent cause of morbidity and mortality among patients with type 1 or type 2 diabetes.
The proposed mechanisms that can link accelerated atherosclerosis and increased cardiovascular risk in this population are poorly understood.
It has been suggested that an association between hyperglycemia and intracellular metabolic changes can result in oxidative stress, low-grade inflammation, and endothelial dysfunction.
Recently, epigenetic factors by different types of reactions are known to be responsible for the interaction between genes and environment and for this reason can also account for the association between diabetes and cardiovascular disease.
The impact of clinical factors that may coexist with diabetes such as obesity, dyslipidemia, and hypertension are also discussed.
Furthermore, evidence that justify screening for subclinical atherosclerosis in asymptomatic patients is controversial and is also matter of this review.
The purpose of this paper is to describe the association between poor glycemic control, oxidative stress, markers of insulin resistance, and of low-grade inflammation that have been suggested as putative factors linking diabetes and cardiovascular disease.
American Psychological Association (APA)
Matheus, Alessandra Saldanha de Mattos& Tannus, Lucianne Righeti Monteiro& Cobas, Roberta Arnoldi& Palma, Catia C. Sousa& Negrato, Carlos Antonio& Gomes, Marilia de Brito. 2013. Impact of Diabetes on Cardiovascular Disease : An Update. International Journal of Hypertension،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-488563
Modern Language Association (MLA)
Matheus, Alessandra Saldanha de Mattos…[et al.]. Impact of Diabetes on Cardiovascular Disease : An Update. International Journal of Hypertension No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-488563
American Medical Association (AMA)
Matheus, Alessandra Saldanha de Mattos& Tannus, Lucianne Righeti Monteiro& Cobas, Roberta Arnoldi& Palma, Catia C. Sousa& Negrato, Carlos Antonio& Gomes, Marilia de Brito. Impact of Diabetes on Cardiovascular Disease : An Update. International Journal of Hypertension. 2013. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-488563
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488563