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Evaluation of the Significance of Pretreatment Liver Biopsy and Baseline Mental Health Disorder Diagnosis on Hepatitis C Treatment Completion Rates at a Veterans Affairs Medical Center
Joint Authors
Kaplan, David E.
O’Flynn, Rose M.
Chang, Kyong-Mi
Kluck, Joseph
Source
Hepatitis Research and Treatment
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
This study was performed to define the overall treatment response rates and treatment completion rates among the population of Hepatitis C infected patients at an urban VA Medical Center.
Additionally, we examined whether pretreatment liver biopsy is a positive predictor for treatment completion and if the presence of mental health disorders is a negative predictor for treatment completion.
Methods.
Retrospective chart review was performed on the 375 patients that were treated for HCV and met the study inclusion parameters between January 1, 2003 and April 1, 2008 at our institution.
Clinical data was obtained from the computerized patient record system and was analyzed for respective parameters.
Results.
Sustained virological response was achieved in 116 (31%) patients.
169 (45%) patients completed a full treatment course.
Also, 44% of patients who received a pre-treatment liver biopsy completed treatment versus 46% completion rates for patients who did not receive a pretreatment liver biopsy.
Baseline ICD9 diagnosis of a mental health disorder was not associated with higher treatment discontinuation rates.
Conclusions.
In conclusion, pretreatment liver biopsy was not a positive predictor for treatment completion, and the presence of mental health disorders was not a negative predictor for treatment completion.
American Psychological Association (APA)
Kluck, Joseph& O’Flynn, Rose M.& Kaplan, David E.& Chang, Kyong-Mi. 2013. Evaluation of the Significance of Pretreatment Liver Biopsy and Baseline Mental Health Disorder Diagnosis on Hepatitis C Treatment Completion Rates at a Veterans Affairs Medical Center. Hepatitis Research and Treatment،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-488583
Modern Language Association (MLA)
Kluck, Joseph…[et al.]. Evaluation of the Significance of Pretreatment Liver Biopsy and Baseline Mental Health Disorder Diagnosis on Hepatitis C Treatment Completion Rates at a Veterans Affairs Medical Center. Hepatitis Research and Treatment No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-488583
American Medical Association (AMA)
Kluck, Joseph& O’Flynn, Rose M.& Kaplan, David E.& Chang, Kyong-Mi. Evaluation of the Significance of Pretreatment Liver Biopsy and Baseline Mental Health Disorder Diagnosis on Hepatitis C Treatment Completion Rates at a Veterans Affairs Medical Center. Hepatitis Research and Treatment. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-488583
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488583