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A Novel Phospholipase A2 (D49) from the Venom of the Crotalus oreganus abyssus (North American Grand Canyon Rattlesnake)
Joint Authors
Albericio, Fernando
Caballol, Maria Antonia O.
Ribeiro, R. I. M. A.
da Silva, Saulo Luís
Honório, Kathia M.
Acosta, Gerardo
de Oliveira, Eliandre
Baldasso, P. A.
Calderon, Leonardo A.
Soares, Andreimar Martins
Maltarollo, Vinícius G.
Martins, W.
Stábeli, R. G.
Carvalho, Bruna M. A.
Marangoni, Sérgio
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-24
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Currently, Crotalus viridis was divided into two species: Crotalus viridis and Crotalus oreganus.
The current classification divides “the old” Crotalus viridis into two new and independent species: Crotalus viridis (subspecies: viridis and nuntius) and Crotalus oreganus (subspecies: abyssus, lutosus, concolor, oreganus, helleri, cerberus, and caliginis).
The analysis of a product from cDNA (E6d), derived from the gland of a specie Crotalus viridis viridis, was found to produce an acid phospholipase A2.
In this study we isolated and characterized a PLA2 (D49) from Crotalus oreganus abyssus venom.
Our studies show that the PLA2 produced from the cDNA of Crotalus viridis viridis (named E6d) is exactly the same PLA2 primary sequence of amino acids isolated from the venom of Crotalus oreganus abyssus.
Thus, the PLA2 from E6d cDNA is actually the same PLA2 presented in the venom of Crotalus oreganus abyssus and does not correspond to the venom from Crotalus viridis viridis.
These facts highlight the importance of performing more studies on subspecies of Crotalus oreganus and Crotalus viridis, since the old classification may have led to mixed results or mistaken data.
American Psychological Association (APA)
Martins, W.& Baldasso, P. A.& Honório, Kathia M.& Maltarollo, Vinícius G.& Ribeiro, R. I. M. A.& Carvalho, Bruna M. A.…[et al.]. 2014. A Novel Phospholipase A2 (D49) from the Venom of the Crotalus oreganus abyssus (North American Grand Canyon Rattlesnake). BioMed Research International،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-488601
Modern Language Association (MLA)
Martins, W.…[et al.]. A Novel Phospholipase A2 (D49) from the Venom of the Crotalus oreganus abyssus (North American Grand Canyon Rattlesnake). BioMed Research International No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-488601
American Medical Association (AMA)
Martins, W.& Baldasso, P. A.& Honório, Kathia M.& Maltarollo, Vinícius G.& Ribeiro, R. I. M. A.& Carvalho, Bruna M. A.…[et al.]. A Novel Phospholipase A2 (D49) from the Venom of the Crotalus oreganus abyssus (North American Grand Canyon Rattlesnake). BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-488601
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488601