Protein Glycosylation in Aspergillus fumigatus Is Essential for Cell Wall Synthesis and Serves as a Promising Model of Multicellular Eukaryotic Development
Author
Source
International Journal of Microbiology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-21, 21 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-28
Country of Publication
Egypt
No. of Pages
21
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Abstract EN
Glycosylation is a conserved posttranslational modification that is found in all eukaryotes, which helps generate proteins with multiple functions.
Our knowledge of glycosylation mainly comes from the investigation of the yeast Saccharomyces cerevisiae and mammalian cells.
However, during the last decade, glycosylation in the human pathogenic mold Aspergillus fumigatus has drawn significant attention.
It has been revealed that glycosylation in A.
fumigatus is crucial for its growth, cell wall synthesis, and development and that the process is more complicated than that found in the budding yeast S.
cerevisiae.
The present paper implies that the investigation of glycosylation in A.
fumigatus is not only vital for elucidating the mechanism of fungal cell wall synthesis, which will benefit the design of new antifungal therapies, but also helps to understand the role of protein glycosylation in the development of multicellular eukaryotes.
This paper describes the advances in functional analysis of protein glycosylation in A.
fumigatus.
American Psychological Association (APA)
Jin, Cheng. 2011. Protein Glycosylation in Aspergillus fumigatus Is Essential for Cell Wall Synthesis and Serves as a Promising Model of Multicellular Eukaryotic Development. International Journal of Microbiology،Vol. 2012, no. 2012, pp.1-21.
https://search.emarefa.net/detail/BIM-488608
Modern Language Association (MLA)
Jin, Cheng. Protein Glycosylation in Aspergillus fumigatus Is Essential for Cell Wall Synthesis and Serves as a Promising Model of Multicellular Eukaryotic Development. International Journal of Microbiology No. 2012 (2012), pp.1-21.
https://search.emarefa.net/detail/BIM-488608
American Medical Association (AMA)
Jin, Cheng. Protein Glycosylation in Aspergillus fumigatus Is Essential for Cell Wall Synthesis and Serves as a Promising Model of Multicellular Eukaryotic Development. International Journal of Microbiology. 2011. Vol. 2012, no. 2012, pp.1-21.
https://search.emarefa.net/detail/BIM-488608
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488608