Olfactory Dysfunction in Patients with Neuromyelitis Optica
Joint Authors
Jarius, Sven
Wildemann, Brigitte
Ruprecht, Klemens
Harms, Lutz
Paul, Friedemann
Schmidt, Felix
Göktas, Önder
Source
Multiple Sclerosis International
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-25
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Neuromyelitis optica (NMO) is a severely disabling autoimmune disorder of the CNS, which mainly affects the optic nerves and spinal cord.
However, recent studies have shown that extra-opticospinal are more common in NMO than previously thought.
Objective.
To investigate olfactory function (OF) in patients with neuromyelitis optica (NMO) versus healthy controls (HC).
Methods.
Psychophysical testing of the orthonasal OF was performed using the Threshold-Discrimination-Identification test (TDI), measuring different qualities of olfaction, in 10 unselected NMO patients and 10 HC.
Results.
Five of 10 NMO patients (50%) showed hyposmia, while all 10 HC were normosmic.
Moreover, NMO patients had significantly lower mean TDI-scores compared to HC, based on a poorer performance in both the Discrimination and the Identification subtests.
Conclusions.
Our results suggest that hyposmia might be part of the expanding clinical spectrum of NMO.
American Psychological Association (APA)
Schmidt, Felix& Göktas, Önder& Jarius, Sven& Wildemann, Brigitte& Ruprecht, Klemens& Paul, Friedemann…[et al.]. 2013. Olfactory Dysfunction in Patients with Neuromyelitis Optica. Multiple Sclerosis International،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-488629
Modern Language Association (MLA)
Schmidt, Felix…[et al.]. Olfactory Dysfunction in Patients with Neuromyelitis Optica. Multiple Sclerosis International No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-488629
American Medical Association (AMA)
Schmidt, Felix& Göktas, Önder& Jarius, Sven& Wildemann, Brigitte& Ruprecht, Klemens& Paul, Friedemann…[et al.]. Olfactory Dysfunction in Patients with Neuromyelitis Optica. Multiple Sclerosis International. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-488629
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488629