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Determinants of Intravascular Resistance in Indian Diabetic Nephropathy Patients : A Hospital-Based Study
Joint Authors
Kumar, Hemant
Thukral, Anubhav
Mishra, Manish
Shukla, Ram Chandra
Srivastava, Vaibhava
Dwivedi, Amit Nandan Dhar
Tripathi, Kamlakar
Source
International Journal of Vascular Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-12
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Aims and Objectives.
Metabolic dysregulation has failed to explain clinical variability of patients with diabetic nephropathy and hence a renewed interest emerged in haemodynamic factors as determinant of progression and development of diabetic nephropathy.
We therefore studied for various factors which can correlate with raised renal vascular resistance in diabetic nephropathy.
Material and Methods.
Renal vascular resistance was measured in patients with established and incipient diabetic nephropathy and compared with controls using noninvasive color Doppler examinations of intrarenal vasculature.
Results.
Renal vascular resistance correlated with age, duration of disease, GFR, serum creatinine, and stage of retinopathy.
Renal vascular resistance was significantly reduced in patients on treatment with RAAS inhibitors and insulin, than those on OHA and antihypertensives other than RAAS inhibitors.
Conclusion.
The study implies that renal vascular resistance may help identify diabetics at high risk of developing nephropathy, and these set of patients could be candidates for RAAS inhibition and early insulin therapy even in patients without albuminuria.
American Psychological Association (APA)
Thukral, Anubhav& Mishra, Manish& Srivastava, Vaibhava& Kumar, Hemant& Dwivedi, Amit Nandan Dhar& Shukla, Ram Chandra…[et al.]. 2011. Determinants of Intravascular Resistance in Indian Diabetic Nephropathy Patients : A Hospital-Based Study. International Journal of Vascular Medicine،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-488688
Modern Language Association (MLA)
Thukral, Anubhav…[et al.]. Determinants of Intravascular Resistance in Indian Diabetic Nephropathy Patients : A Hospital-Based Study. International Journal of Vascular Medicine No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-488688
American Medical Association (AMA)
Thukral, Anubhav& Mishra, Manish& Srivastava, Vaibhava& Kumar, Hemant& Dwivedi, Amit Nandan Dhar& Shukla, Ram Chandra…[et al.]. Determinants of Intravascular Resistance in Indian Diabetic Nephropathy Patients : A Hospital-Based Study. International Journal of Vascular Medicine. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-488688
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488688