Complete Remission of Methotrexate-Related Epstein-Barr-Virus-Associated Hodgkin-Like Lymphoma following Withdrawal of MTX Coupled with Clarithromycin Administration

Joint Authors

Kaneko, Hiroyuki
Nakamura, Masaya
Takemori, Nobuo
Kojima, Masaru

Source

Case Reports in Hematology

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2012-12-19

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Diseases

Abstract EN

Patients with rheumatoid arthritis (RA) are known to develop lymphoproliferative disorders (LPDs) during the course of illness, particularly in cases treated with methotrexate (MTX) for long periods.

We describe a case of MTX-related Epstein-Barr-virus-(EBV-) associated LPD resembling Hodgkin’s lymphoma (HL), in which a dramatic complete remission was achieved after withdrawal of MTX coupled with clarithromycin (CAM) administration.

Withdrawal of MTX coupled with CAM administration seemed to be effective for treating MTX-related EBV-associated LPDs.

In particular, an immunomodulative effect of CAM might have been involved in achieving complete remission.

American Psychological Association (APA)

Takemori, Nobuo& Kaneko, Hiroyuki& Nakamura, Masaya& Kojima, Masaru. 2012. Complete Remission of Methotrexate-Related Epstein-Barr-Virus-Associated Hodgkin-Like Lymphoma following Withdrawal of MTX Coupled with Clarithromycin Administration. Case Reports in Hematology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-488932

Modern Language Association (MLA)

Takemori, Nobuo…[et al.]. Complete Remission of Methotrexate-Related Epstein-Barr-Virus-Associated Hodgkin-Like Lymphoma following Withdrawal of MTX Coupled with Clarithromycin Administration. Case Reports in Hematology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-488932

American Medical Association (AMA)

Takemori, Nobuo& Kaneko, Hiroyuki& Nakamura, Masaya& Kojima, Masaru. Complete Remission of Methotrexate-Related Epstein-Barr-Virus-Associated Hodgkin-Like Lymphoma following Withdrawal of MTX Coupled with Clarithromycin Administration. Case Reports in Hematology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-488932

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-488932