Familial Renal Cancer : Molecular Genetics and Surgical Management
Joint Authors
Singer, Eric A.
Rosner, Inger L.
Linehan, W. Marston
Barrisford, Glen W.
Bratslavsky, Gennady
Source
International Journal of Surgical Oncology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-22
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Familial renal cancer (FRC) is a heterogeneous disorder comprised of a variety of subtypes.
Each subtype is known to have unique histologic features, genetic alterations, and response to therapy.
Through the study of families affected by hereditary forms of kidney cancer, insights into the genetic basis of this disease have been identified.
This has resulted in the elucidation of a number of kidney cancer gene pathways.
Study of these pathways has led to the development of novel targeted molecular treatments for patients affected by systemic disease.
As a result, the treatments for families affected by von Hippel-Lindau (VHL), hereditary papillary renal carcinoma (HPRC), hereditary leiomyomatosis renal cell carcinoma (HLRCC), and Birt-Hogg-Dubé (BHD) are rapidly changing.
We review the genetics and contemporary surgical management of familial forms of kidney cancer.
American Psychological Association (APA)
Barrisford, Glen W.& Singer, Eric A.& Rosner, Inger L.& Linehan, W. Marston& Bratslavsky, Gennady. 2011. Familial Renal Cancer : Molecular Genetics and Surgical Management. International Journal of Surgical Oncology،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-488936
Modern Language Association (MLA)
Rosner, Inger L.…[et al.]. Familial Renal Cancer : Molecular Genetics and Surgical Management. International Journal of Surgical Oncology No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-488936
American Medical Association (AMA)
Barrisford, Glen W.& Singer, Eric A.& Rosner, Inger L.& Linehan, W. Marston& Bratslavsky, Gennady. Familial Renal Cancer : Molecular Genetics and Surgical Management. International Journal of Surgical Oncology. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-488936
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488936