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Histologically Measured Cardiomyocyte Hypertrophy Correlates with Body Height as Strongly as with Body Mass Index
Joint Authors
Tracy, Richard E.
Sander, Gary E.
Source
Cardiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Cardiac myocytes are presumed to enlarge with left ventricular hypertrophy (LVH).
This study correlates histologically measured myocytes with lean and fat body mass.
Cases of LVH without coronary heart disease and normal controls came from forensic autopsies.
The cross-sectional widths of myocytes in H&E-stained paraffin sections followed log normal distributions almost to perfection in all 104 specimens, with constant coefficient of variation across the full range of ventricular weight, as expected if myocytes of all sizes contribute proportionately to hypertrophy.
Myocyte sizes increased with height.
By regression analysis, height2.7 as a proxy for lean body mass and body mass index (BMI) as a proxy for fat body mass, exerted equal effects in the multiple correlation with myocyte volume, and the equation rejected race and sex.
In summary, myocyte sizes, as indexes of LVH, suggest that lean and fat body mass may contribute equally.
American Psychological Association (APA)
Tracy, Richard E.& Sander, Gary E.. 2011. Histologically Measured Cardiomyocyte Hypertrophy Correlates with Body Height as Strongly as with Body Mass Index. Cardiology Research and Practice،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-488952
Modern Language Association (MLA)
Tracy, Richard E.& Sander, Gary E.. Histologically Measured Cardiomyocyte Hypertrophy Correlates with Body Height as Strongly as with Body Mass Index. Cardiology Research and Practice No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-488952
American Medical Association (AMA)
Tracy, Richard E.& Sander, Gary E.. Histologically Measured Cardiomyocyte Hypertrophy Correlates with Body Height as Strongly as with Body Mass Index. Cardiology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-488952
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-488952