Social-Cognitive Bias and Depressive Symptoms in Outpatients with Bipolar Disorder

Abstract EN

A deficit of social cognition in bipolar disorder has been shown, even when patients are stable.

This study compares the attribution of intentions (social-cognitive bias) in a group of 37 outpatients with bipolar disorder with 32 matched control subjects.

Bipolar patients scored significantly higher in the Ambiguous Intentions Hostility Questionnaire, showing an angry and intentionality bias (P=.001, P=.02).

Differences in blame scale and hostility bias did not reach statistical significance, but a trend was found (P=.06).

Bipolar patients with depressive symptoms presented a higher score in the angry bias scale (P=.03) and aggressivity bias scale (P=.004).

The global functioning (GAF) correlates significantly with intentionality (P=.005), angry (P=.027), and aggressivity (P=.020) biases.

Bipolar patients show a social-cognitive bias that may play a role in their functional outcome.