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Arthroscopic Optical Coherence Tomography in Diagnosis of Early Arthritis
Joint Authors
Chu, Constance R.
O'Malley, Michael J.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Osteoarthritis (OA) is a progressive, debilitating disease that is increasing in prevalence.
The pathogenesis of OA is likely multifactorial but ultimately leads to progressive breakdown of collagen matrix and loss of chondrocytes.
Current clinical modalities employed to evaluate cartilage health and diagnose osteoarthritis in orthopaedic surgery include, radiography, MRI, and arthroscopy.
While these assessment methods can show cartilage fissuring and loss, they are limited in ability to diagnose cartilage injury and degeneration prior breakdown of the articular surface.
An improved clinical ability to detect subsurface cartilage pathology is important for development and testing of chondroprotective and chondrorestorative treatments because the pathological changes following surface breakdown are generally considered to be irreversible.
Optical Coherence Tomography (OCT), is a novel, non-destructive imaging technology capable of near-real time cross-sectional images of articular cartilage at high resolutions comparable to low power histology.
This review discusses a series of bench to bedside studies supporting the potential use of OCT for enhanced clinical diagnosis and staging of early cartilage injury and degeneration.
OCT was also found to be useful as a translations research tool to assist in clinical evaluation of novel quantitative MRI technologies for non-invasive evaluation of articular cartilage.
American Psychological Association (APA)
O'Malley, Michael J.& Chu, Constance R.. 2011. Arthroscopic Optical Coherence Tomography in Diagnosis of Early Arthritis. Minimally Invasive Surgery،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-489186
Modern Language Association (MLA)
O'Malley, Michael J.& Chu, Constance R.. Arthroscopic Optical Coherence Tomography in Diagnosis of Early Arthritis. Minimally Invasive Surgery No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-489186
American Medical Association (AMA)
O'Malley, Michael J.& Chu, Constance R.. Arthroscopic Optical Coherence Tomography in Diagnosis of Early Arthritis. Minimally Invasive Surgery. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-489186
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-489186