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Medial Orbitofrontal Cortex Is Associated with Fatigue Sensation
Joint Authors
Ouchi, Yasuomi
Onoe, Hirotaka
Watanabe, Yasuyoshi
Yamamoto, Shigeyuki
Kataoka, Yosky
Iwase, Masao
Tanaka, Masaaki
Okada, Hiroyuki
Tsukada, Hideo
Yoshikawa, Etsuji
Kuratsune, Hirohiko
Tajima, Seiki
Source
Neurology Research International
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Fatigue is an indispensable bioalarm to avoid exhaustive state caused by overwork or stresses.
It is necessary to elucidate the neural mechanism of fatigue sensation for managing fatigue properly.
We performed H2O 15 positron emission tomography scans to indicate neural activations while subjects were performing 35-min fatigue-inducing task trials twice.
During the positron emission tomography experiment, subjects performed advanced trail-making tests, touching the target circles in sequence located on the display of a touch-panel screen.
In order to identify the brain regions associated with fatigue sensation, correlation analysis was performed using statistical parametric mapping method.
The brain region exhibiting a positive correlation in activity with subjective sensation of fatigue, measured immediately after each positron emission tomography scan, was located in medial orbitofrontal cortex (Brodmann's area 10/11).
Hence, the medial orbitofrontal cortex is a brain region associated with mental fatigue sensation.
Our findings provide a new perspective on the neural basis of fatigue.
American Psychological Association (APA)
Tajima, Seiki& Yamamoto, Shigeyuki& Tanaka, Masaaki& Kataoka, Yosky& Iwase, Masao& Yoshikawa, Etsuji…[et al.]. 2010. Medial Orbitofrontal Cortex Is Associated with Fatigue Sensation. Neurology Research International،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-489199
Modern Language Association (MLA)
Tajima, Seiki…[et al.]. Medial Orbitofrontal Cortex Is Associated with Fatigue Sensation. Neurology Research International No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-489199
American Medical Association (AMA)
Tajima, Seiki& Yamamoto, Shigeyuki& Tanaka, Masaaki& Kataoka, Yosky& Iwase, Masao& Yoshikawa, Etsuji…[et al.]. Medial Orbitofrontal Cortex Is Associated with Fatigue Sensation. Neurology Research International. 2010. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-489199
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-489199